Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein. - Wikidata - awgldk - TriplyDB

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein.

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein.

http://www.wikidata.org/entity/Q35079502

about

UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation The role of ALFY in selective autophagy You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia Autophagy in malignant transformation and cancer progression Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins.Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner Identification of JL1037 as a novel, specific, reversible lysine-specific demethylase 1 inhibitor that induce apoptosis and autophagy of AML cells WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells.Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives.MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia.p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells.The adaptor protein p62 is involved in RANKL-induced autophagy and osteoclastogenesis.The generation of neutrophils in the bone marrow is controlled by autophagy Reactive oxygen species regulate the differentiation of acute promyelocytic leukemia cells through HMGB1-mediated autophagy PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway.ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells.Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells.Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity.The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide Autophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors.Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cells New Strategies to Direct Therapeutic Targeting of PML to Treat Cancers All-Trans Retinoic Acid Modulates DNA Damage Response and the Expression of the VEGF-A and MKI67 Genes in ARPE-19 Cells Subjected to Oxidative Stress Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation Transactivation of Atg4b by C/EBPβ promotes autophagy to facilitate adipogenesis.Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model.Role of autophagy in acute myeloid leukemia therapy.Rationale and efficacy of proteasome inhibitor combined with arsenic trioxide in the treatment of acute promyelocytic leukemia.Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells Extracellular DNA traps released by acute promyelocytic leukemia cells through autophagy Tazarotene-Induced Gene 1 Enhanced Cervical Cell Autophagy through Transmembrane Protein 192 The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging.Is PML a Tumor Suppressor?Retinoid receptor signaling and autophagy in acute promyelocytic leukemia.Considering autophagy, β-Catenin and E-Cadherin as innovative therapy aspects in AML.Autophagy governs erythroid differentiation both in vitro and in vivo.

P2860

Q24304043-3A91347D-A706-4074-913E-922D8B1CE5AC Q26828736-188A62D5-E3D3-49F9-8B5D-8B1F4B943F1D Q26998971-CFDBC4B7-CD89-4D4F-9D97-448ADA87F4D7 Q27000191-E215AB18-45BE-41FA-B3B3-BB4C7B62FFC0 Q28301777-E55DFDCD-0275-4428-A047-19BCCB168243 Q33577569-2F87410F-13F0-4B7D-9357-5E8B1184FE53 Q33707343-5110BEA7-D356-48D8-92DD-37CFABEB60FC Q33761948-3A5F4BEE-8655-4D80-B6B4-7FA1E3113DCE Q34007677-96C216D2-5D4D-46C9-96A5-65CD7AC18D46 Q34339147-8493903B-B3FE-407E-BB6A-12C5E5DFC012 Q34344666-5522B79F-C22A-40A5-8A1C-76E86368F8B2 Q34486392-269F63A6-26D2-4033-9ACE-DB78A4582509 Q34572745-C759A145-2999-4147-B115-90FE636B44FB Q35079492-0DF35637-7298-4EF6-8359-858582667160 Q35402749-A6B76B33-CD5E-4F57-8DFC-7163C99413CA Q35534091-A349BF67-0D74-44B8-8C34-D11BF315F344 Q35623353-88704690-F46B-4F87-AFEC-0A6A8DA1563A Q35781485-377E3210-367D-4BAC-9686-356821D7E311 Q35970498-7F8D5577-CACD-492A-A7F8-1B22B613CB5D Q36022328-C3545384-A8B4-43F9-B0E6-6A157C181754 Q36111614-F09A34D3-CF35-4694-9B6C-2F21BCB53B8D Q36352545-0BB48B35-4676-489B-8C1E-072CBD685846 Q36556257-4F3203A8-5148-45CF-82F8-4D9E893860EA Q36662342-9394724F-288C-404B-800E-A3A7C717F680 Q36850742-7B1EF2D2-293F-474A-8C57-3EFF00BEC339 Q37050682-6A7DF736-A2B3-42F4-A080-9122B48AD4F9 Q37103762-5DC9BCA4-5F07-43E9-8FF8-03A60EA52253 Q37122897-400D0095-696E-4B1D-A732-8A1356C959CD Q37330859-D1AD7322-3969-4B4A-819B-E80A8F71DBD5 Q37354063-FACA76D7-3D9B-447C-AEB7-1DEAD19400CA Q37396013-78781233-588B-41EC-BE89-7959DE79ADCD Q37409768-CE3CE14E-F49F-4B86-A248-34B9BB7556BF Q37412545-3A7D2C68-24A2-47FF-B271-929FF6F9868A Q37575776-DBCD0391-0323-40E0-AB36-3758095A66C9 Q37633708-899CBE09-8C7E-4BC8-9FF6-4EF8DD805E47 Q38016322-CF65B846-3D67-4677-989F-9FAB35227758 Q38121090-B0C58AEE-CDCC-4F7E-8109-7F3F85838F74 Q38201532-E0B55EAD-219C-40C6-8791-5F8BBA73D6DA Q38824005-4B0C2518-EBC6-43D2-BC29-69EB9CE7F0DE Q38859056-D35EEB4B-A014-4E78-82AC-C6EAB7CD0713

P2860

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein.

http://www.wikidata.org/entity/Q35079502

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@ast

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@en

type

label

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@ast

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@en

prefLabel

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@ast

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@en

P1433

Q35079502-5F8174DF-F885-4393-B0DB-3CF0E366729C

P1476

Q35079502-A26772F9-9D44-4149-A68E-BF049FC6C58D

P2093

Q35079502-0949DFCB-D31A-4C2C-BEEF-C6842398F2DD

Q35079502-281A5BF3-95EF-4325-B8CC-FC3B1A7BBF1E

Q35079502-32F37165-8B6D-49E5-BBCC-0BB9CD11D004

Q35079502-4AC9C68A-EB32-43C6-B929-E24CE80A1F6D

Q35079502-4ADD1486-FDA3-49DE-B076-7985EDD60D10

Q35079502-7AE85810-D029-4F94-93FD-2BD9436E3FEC

Q35079502-7C24BEA8-A9DC-4B31-A9A2-78EF34310921

Q35079502-8131872A-5AE3-43BA-8CEF-397B32C82BD4

Q35079502-8524D3D6-A3E6-4913-B0C1-018D7445185A

Q35079502-C80474E2-195A-4D71-83EE-C66C49D43D27

P2860

Q35079502-0517DE65-80FB-4107-AEBF-59D26F851767

Q35079502-0B4F63B8-DAC9-4C39-9EDB-75B8D6620ABD

Q35079502-0E6CAEC2-E9B5-47F0-AEF4-C4B9C9009953

Q35079502-0FDA92DC-B05C-44CE-B899-6C4F8DF2F64C

Q35079502-154613F1-80AD-4681-921D-60DA3F607CC1

Q35079502-1AEFF132-1E33-4FBC-A112-A6A167D945D8

Q35079502-1DBCD09E-1CFC-4910-B541-6E5C80D688F1

Q35079502-20FFEED2-9F7E-4E93-B9AB-81D40E770D94

Q35079502-25EFCD71-9D21-4C30-8EB1-0EBEC9F8047E

Q35079502-28B8E26F-389E-42C7-B0B3-E9216F1D572B

P304

Q35079502-CEF53328-1869-4AF3-AEE2-9221AFF64845

P31

Q35079502-0544D75D-2E2C-4196-B1FE-02C9260A1709

P356

Q35079502-D0CF9DBF-EE7E-48EE-8C78-A8D54B8E7562

P433

Q35079502-56761C55-920E-4F0B-8B87-7E30EB5390CA

P478

Q35079502-47C4024B-93F3-496D-8B92-317484909D86

P577

Q35079502-0C723287-839F-4B15-A336-8290908B6E1E

P5875

Q35079502-4136BCD7-95A7-4ADE-9ED6-7181F13045CB

P698

Q35079502-25B8698B-29A8-4079-B649-076C4A3AF841

P921

Q35079502-6728C5B5-B0BC-44C2-9BE9-6F56906C90F9

P932

Q35079502-04FE5024-B4B5-4324-9EE3-1FCD44BCAA84

P356

P1433

P1476

Autophagy regulates myeloid ce ...... ation of PML-RARα oncoprotein.

@en

P2093

Daolin Tang

http://www.w3.org/2001/XMLSchema#string

Kristen M Livesey

http://www.w3.org/2001/XMLSchema#string

Liying Liu

http://www.w3.org/2001/XMLSchema#string

Lizhi Cao

http://www.w3.org/2001/XMLSchema#string

Min Xie

http://www.w3.org/2001/XMLSchema#string

Minghua Yang

http://www.w3.org/2001/XMLSchema#string

Rui Kang

http://www.w3.org/2001/XMLSchema#string

Xiaocheng Yin

http://www.w3.org/2001/XMLSchema#string

Yan Yu

http://www.w3.org/2001/XMLSchema#string

Yiming Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Endogenous HMGB1 regulates autophagy

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

mTOR regulates memory CD8 T-cell differentiation

Autophagy suppresses tumorigenesis through elimination of p62

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection

Autophagy in the Pathogenesis of Disease

TOR, a central controller of cell growth.

Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia

P304

401-411

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4161/AUTO.7.4.14397

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

2011-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49711204

http://www.w3.org/2001/XMLSchema#string

P698

21187718

http://www.w3.org/2001/XMLSchema#string

P921

P932

3127220

http://www.w3.org/2001/XMLSchema#string