Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide
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The Philadelphia chromosome in leukemogenesisManagement of Chronic Myeloid Leukemia Patients Resistant to Tyrosine Kinase Inhibitors TreatmentThe different roles of selective autophagic protein degradation in mammalian cellsAutophagy in malignant transformation and cancer progressionAutophagy-Regulating microRNAs and CancerAutophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins.Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targetingIdentification of JL1037 as a novel, specific, reversible lysine-specific demethylase 1 inhibitor that induce apoptosis and autophagy of AML cellsp62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells.IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes.Targeting catalase but not peroxiredoxins enhances arsenic trioxide-induced apoptosis in K562 cells.Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemiaAlternative approaches to eradicating the malignant clone in chronic myeloid leukemia: tyrosine-kinase inhibitor combinations and beyond.Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma.MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation.Dissecting the pathways that destabilize mutant p53: the proteasome or autophagy?The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer.Regulation of the kinase RSK1 by arsenic trioxide and generation of antileukemic responsesATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells.Targeting survival pathways in chronic myeloid leukaemia stem cellsResveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors.Chronic myeloid leukemia: overview of new agents and comparative analysis.Autophagy in blood cancers: biological role and therapeutic implications.Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy.Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.VEGF depletion enhances bcr-abl-specific sensitivity of arsenic trioxide in chronic myelogenous leukemia.Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells.Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein.Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cellsTargeting oncoproteins for degradation by small molecules in myeloid leukemia.Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.Targeting Autophagy in ALK-Associated Cancers.Armillaridin induces autophagy-associated cell death in human chronic myelogenous leukemia K562 cells.[The yin and the yang of autophagy in cancer cells].Autophagy in cancer biology and therapyThe Ins and Outs of Autophagy and Metabolism in Hematopoietic and Leukemic Stem Cells: Food for ThoughtCombination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3
P2860
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P2860
Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Autophagic degradation of the ...... responses by arsenic trioxide
@ast
Autophagic degradation of the ...... responses by arsenic trioxide
@en
type
label
Autophagic degradation of the ...... responses by arsenic trioxide
@ast
Autophagic degradation of the ...... responses by arsenic trioxide
@en
prefLabel
Autophagic degradation of the ...... responses by arsenic trioxide
@ast
Autophagic degradation of the ...... responses by arsenic trioxide
@en
P2093
P2860
P1433
P1476
Autophagic degradation of the ...... responses by arsenic trioxide
@en
P2093
Bhumika Sharma
Dennis J Goussetis
Edward J Wu
Elias Gounaris
Eliza Vakana
Jessica K Altman
Leonidas C Platanias
P2860
P304
P356
10.1182/BLOOD-2012-01-402578
P407
P577
2012-08-16T00:00:00Z