about
Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phaseEndoreplication: polyploidy with purposeE2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loopRetinoblastoma family genesEndoreplicationAtypical E2F repressors and activators coordinate placental developmentHid arbitrates collective cell death in the Drosophila wing.Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor.Context-dependent requirement for dE2F during oncogenic proliferationElucidation of functional consequences of signalling pathway interactions.Division and apoptosis of E2f-deficient retinal progenitorsE2F1 regulates cellular growth by mTORC1 signaling.A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo.dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes.Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2Genome-wide expression analysis identifies a modulator of ionizing radiation-induced p53-independent apoptosis in Drosophila melanogasterSpotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phaseS phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues.Mutation of the DEAD-box helicase belle downregulates the cyclin-dependent kinase inhibitor Dacapo.The retinoblastoma protein regulates pericentric heterochromatin.Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells.The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.Emerging roles of E2Fs in cancer: an exit from cell cycle controlTargeting Rb inactivation in cancers by synthetic lethality.The rb pathway and cancer therapeuticsTranscription factor networks in Drosophila melanogaster.RBF and Rno promote photoreceptor differentiation onset through modulating EGFR signaling in the Drosophila developing eyeThe ancient function of RB-E2F pathway: insights from its evolutionary historyControl of Drosophila endocycles by E2F and CRL4(CDT2).The E2F family: specific functions and overlapping interestsCell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway.Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cellsThe atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.E2fl1 is a meiosis-specific transcription factor in the protist Tetrahymena thermophila.dE2F2-independent rescue of proliferation in cells lacking an activator dE2F1.Evidence for autoregulation and cell signaling pathway regulation from genome-wide binding of the Drosophila retinoblastoma protein.RBF binding to both canonical E2F targets and noncanonical targets depends on functional dE2F/dDP complexesTombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early.Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Functional antagonism between E2F family members
@ast
Functional antagonism between E2F family members
@en
type
label
Functional antagonism between E2F family members
@ast
Functional antagonism between E2F family members
@en
prefLabel
Functional antagonism between E2F family members
@ast
Functional antagonism between E2F family members
@en
P2093
P2860
P356
P1433
P1476
Functional antagonism between E2F family members
@en
P2093
K Balczarek-Strang
M V Frolov
P2860
P304
P356
10.1101/GAD.903901
P577
2001-08-01T00:00:00Z