A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor
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Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressorMutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinsEvi-1 transforming and repressor activities are mediated by CtBP co-repressor proteinsThe LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityRBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genesThe human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth.Highlight: BRCA1 and BRCA2 proteins in breast cancerNuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin geneAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayThe interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIFAssociation of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factorIkaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activitySIAH-1 interacts with CtIP and promotes its degradation by the proteasome pathwayThe CtBP family: enigmatic and enzymatic transcriptional co-repressorsIkaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repressionpRb2/p130: a new candidate for retinoblastoma tumor formationInteraction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.Regulation of neuron survival and death by p130 and associated chromatin modifiers.Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding proteinTwo nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminal-binding protein (CtBP)Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiencyA role for E2F6 in distinguishing G1/S- and G2/M-specific transcriptionBinding of neuronal nitric-oxide synthase (nNOS) to carboxyl-terminal-binding protein (CtBP) changes the localization of CtBP from the nucleus to the cytosol: a novel function for targeting by the PDZ domain of nNOSInteraction with cyclin H/cyclin-dependent kinase 7 (CCNH/CDK7) stabilizes C-terminal binding protein 2 (CtBP2) and promotes cancer cell migrationRole of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression.Interaction of the E1A oncoprotein with Yak1p, a novel regulator of yeast pseudohyphal differentiation, and related mammalian kinases.Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins.Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3CLoss of full length CtBP1 expression enhances the invasive potential of human melanoma.Rb function in cell-cycle regulation and apoptosis.Mutations in the BRCT binding site of BRCA1 result in hyper-recombinationEstablishment of irreversible growth arrest in myogenic differentiation requires the RB LXCXE-binding function.dCtBP-dependent and -independent repression activities of the Drosophila Knirps proteinBeta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator.Role of the E1A Rb-binding domain in repression of the NF-kappa B-dependent defense against tumor necrosis factor-alphaDistinctions in the specificity of E2F function revealed by gene expression signatures.PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure.Lessons learned from BRCA1 and BRCA2.RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.
P2860
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P2860
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@ast
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@en
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@nl
type
label
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@ast
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@en
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@nl
prefLabel
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@ast
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@en
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@nl
P2093
P2860
P3181
P356
P1476
A mechanism for Rb/p130-mediat ...... itment of the CtBP corepressor
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.96.17.9574
P407
P577
1999-08-17T00:00:00Z