The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA.
about
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability.RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usageRNA binding protein sex-lethal (Sxl) and control of Drosophila sex determination and dosage compensationShared RNA-binding sites for interacting members of the Drosophila ELAV family of neuronal proteins.RNA-binding proteins in eye development and disease: implication of conserved RNA granule componentsInterkingdom complementation reveals structural conservation and functional divergence of 14-3-3 proteinsIncrease of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memoryThe C2H2 zinc-finger protein SYD-9 is a putative posttranscriptional regulator for synaptic transmissionEvolution of Nova-dependent splicing regulation in the brainComparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines.Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignanoDrosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolismThe Drosophila Wilms׳ Tumor 1-Associating Protein (WTAP) homolog is required for eye development.Conditional gene expression and RNAi using MEC-8-dependent splicing in C. elegans.ELAV multimerizes on conserved AU4-6 motifs important for ewg splicing regulation.The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous systemA nuclear function of Hu proteins as neuron-specific alternative RNA processing regulatorsELAV-mediated 3'-end processing of ewg transcripts is evolutionarily conserved despite sequence degeneration of the ELAV-binding site.Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites.Concentration and Localization of Coexpressed ELAV/Hu Proteins Control Specificity of mRNA Processing.ELAV mediates 3' UTR extension in the Drosophila nervous system.ELAV inhibits 3'-end processing to promote neural splicing of ewg pre-mRNAThe third RNA recognition motif of Drosophila ELAV protein has a role in multimerization.Transcription-coupled and splicing-coupled strand asymmetries in eukaryotic genomes.Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesisNeuronal ELAVL proteins utilize AUF-1 as a co-partner to induce neuron-specific alternative splicing of APPThe complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins.Alternative splicing in Drosophila neuronal development.RNA-binding protein research with transcriptome-wide technologies in neural development.Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing.Alternative polyadenylation coupled to transcription initiation: Insights from ELAV-mediated 3' UTR extension.Diverse regulation of 3' splice site usage.Altered translational repression of an RNA-binding protein, Elav by AOA2-causative Senataxin mutation.Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.Coactivator-associated arginine methyltransferase 1, CARM1, affects pre-mRNA splicing in an isoform-specific manner.Regulation of neuron-specific alternative splicing of neurofibromatosis type 1 pre-mRNA.ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervous system.The Snail family member Worniu is continuously required in neuroblasts to prevent Elav-induced premature differentiationRegulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins.Neural specificity of the RNA-binding protein Elav is achieved by post-transcriptional repression in non-neural tissues.
P2860
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P2860
The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA.
description
2001 nĆ® lÅ«n-bĆ»n
@nan
2001 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕøÕÆÕæÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
2001 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÕæÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2001幓ć®č«ę
@ja
2001幓č«ę
@yue
2001幓č«ę
@zh-hant
2001幓č«ę
@zh-hk
2001幓č«ę
@zh-mo
2001幓č«ę
@zh-tw
2001幓č®ŗę
@wuu
name
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@ast
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@en
type
label
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@ast
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@en
prefLabel
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@ast
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@en
P2093
P2860
P356
P1433
P1476
The neuron-specific RNA-bindin ...... inds directly to its pre-mRNA.
@en
P2093
P2860
P304
P356
10.1101/GAD.903101
P577
2001-10-01T00:00:00Z