Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
about
Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stabilityRNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usageThe structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA bindingCARM1 regulates proliferation of PC12 cells by methylating HuDIncrease of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memoryThe insulin-like growth factor mRNA binding-protein IMP-1 and the Ras-regulatory protein G3BP associate with tau mRNA and HuD protein in differentiated P19 neuronal cells.Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignanoNovel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets.ELAV multimerizes on conserved AU4-6 motifs important for ewg splicing regulation.The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs.A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulatorsELAV-mediated 3'-end processing of ewg transcripts is evolutionarily conserved despite sequence degeneration of the ELAV-binding site.HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA.Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins.ELAV inhibits 3'-end processing to promote neural splicing of ewg pre-mRNAThe third RNA recognition motif of Drosophila ELAV protein has a role in multimerization.All three RNA recognition motifs and the hinge region of HuC play distinct roles in the regulation of alternative splicing.Diverse molecular functions of Hu proteins.Neuronal ELAVL proteins utilize AUF-1 as a co-partner to induce neuron-specific alternative splicing of APPThe complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins.Trans-acting factors governing acetylcholinesterase mRNA metabolism in neurons.Mechanisms coordinating ELAV/Hu mRNA regulons.Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunctionSynaptic control of local translation: the plot thickens with new characters.Regulation of ELAV/Hu RNA-binding proteins by phosphorylation.Hu Antigen R (HuR) multimerization contributes to glioma disease progression.Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element.Translational control of tumor necrosis factor-related apoptosis-inducing ligand death receptor expression in melanoma cells.Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas.Functional and direct interaction between the RNA binding protein HuD and active Akt1.RhoB mRNA is stabilized by HuR after UV light.Xenopus ElrB, but not ElrA, binds RNA as an oligomer: possible role of the linker.Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approachUnraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated Factors
P2860
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P2860
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@en
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@nl
type
label
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@en
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@nl
prefLabel
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@en
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@nl
P2093
P2860
P356
P1476
Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
@en
P2093
Eiji Sakashita
Hiroshi Sakamoto
Katsumi Kasashima
Kuniaki Saito
P2860
P304
P356
10.1093/NAR/GKF567
P407
P577
2002-10-01T00:00:00Z