Antigen receptor selection by editing or downregulation of V(D)J recombination.
about
Design of synthetic antibody libraries.Mechanisms of self-nonself discrimination and possible clinical relevance.Clonally stable Vκ allelic choice instructs Igκ repertoire.Potential roles of activation-induced cytidine deaminase in promotion or prevention of autoimmunity in humansT cells from epicutaneously immunized mice are prone to T cell receptor revisionB cell receptor signaling-based index as a biomarker for the loss of peripheral immune tolerance in autoreactive B cells in rheumatoid arthritis.T-cell receptor revision: friend or foe?A stepwise epigenetic process controls immunoglobulin allelic exclusion.Receptor editing in lymphocyte development and central tolerance.Epigenetic regulation of monoallelic rearrangement (allelic exclusion) of antigen receptor genes.The molecular basis and biological significance of VH replacement.V(H) replacement in rearranged immunoglobulin genes.Cellular and genetic mechanisms of self tolerance and autoimmunity.CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance.Potential contribution of VH gene replacement in immunity and disease.Primer: mechanisms of immunologic tolerance.Molecular, biologic, and pharmacokinetic properties of monoclonal antibodies: impact of these parameters on early clinical development.Regulation of VH replacement by B cell receptor-mediated signaling in human immature B cellsNegative selection, not receptor editing, is a physiological response of autoreactive thymocytes.Role of recombination activating genes in the generation of antigen receptor diversity and beyond.B cell biology: an overview.Food-Nonfood Discrimination in Ancestral Vertebrates: Gamete Cannibalism and the Origin of the Adaptive Immune System.Integrated mimicry of B cell antibody mutagenesis using yeast homologous recombinationStage-specific expression of DNasegamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.RasGRP1 sensitizes an immature B cell line to antigen receptor-induced apoptosis.Receptor revision of immunoglobulin heavy chain genes in human MALT lymphomas.A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.Natural (auto)antibodies in calves are affected by age and diet.
P2860
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P2860
Antigen receptor selection by editing or downregulation of V(D)J recombination.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Antigen receptor selection by editing or downregulation of V(D)J recombination.
@ast
Antigen receptor selection by editing or downregulation of V(D)J recombination.
@en
type
label
Antigen receptor selection by editing or downregulation of V(D)J recombination.
@ast
Antigen receptor selection by editing or downregulation of V(D)J recombination.
@en
prefLabel
Antigen receptor selection by editing or downregulation of V(D)J recombination.
@ast
Antigen receptor selection by editing or downregulation of V(D)J recombination.
@en
P1476
Antigen receptor selection by editing or downregulation of V(D)J recombination
@en
P2093
David Nemazee
P304
P356
10.1016/S0952-7915(03)00008-6
P577
2003-04-01T00:00:00Z