Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study. - Wikidata - awgldk - TriplyDB

Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study.

Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study.

http://www.wikidata.org/entity/Q35085729

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Ketamine and other glutamate receptor modulators for depression in adults Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches Negative Allosteric Modulators of Metabotropic Glutamate Receptors Subtype 5 in Addiction: a Therapeutic Window Cell atrophy and loss in depression: reversal by antidepressant treatment GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.Imaging glutamate in schizophrenia: review of findings and implications for drug discovery.Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder Test-retest reproducibility of the metabotropic glutamate receptor 5 ligand [¹⁸F]FPEB with bolus plus constant infusion in humans Gene expression analysis of novel genes in the prefrontal cortex of major depressive disorder subjects.Imaging glutamate homeostasis in cocaine addiction with the metabotropic glutamate receptor 5 positron emission tomography radiotracer [(11)C]ABP688 and magnetic resonance spectroscopy Decreased occipital cortical glutamate levels in response to successful cognitive-behavioral therapy and pharmacotherapy for major depressive disorder.Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics.New targets for rapid antidepressant action.Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression.In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [(11) C]ABP688 PET imaging In vivo imaging of mGluR5 changes during epileptogenesis using [11C]ABP688 PET in pilocarpine-induced epilepsy rat model The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder The role of metabotropic glutamate receptor 5 in the pathogenesis of mood disorders and addiction: combining preclinical evidence with human Positron Emission Tomography (PET) studies.An excitatory synapse hypothesis of depression Comparative assessment of parametric neuroreceptor mapping approaches based on the simplified reference tissue model using [¹¹C]ABP688 PET.Major depressive disorder and alterations in insular cortical activity: a review of current functional magnetic imaging research.Reduced phosphorylation of the mTOR signaling pathway components in the amygdala of rats exposed to chronic stress.Novel Glutamatergic Treatments for Severe Mood Disorders.Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [11C]ABP688 positron emission tomography GABAergic control of depression-related brain states Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: an autoradiographic study.mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway.Studies of the metabotropic glutamate receptor 5 radioligand [¹¹C]ABP688 with N-acetylcysteine challenge in rhesus monkeys.The Emerging Role of Metabotropic Glutamate Receptors in the Pathophysiology of Chronic Stress-Related Disorders Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging.Characterization of brain mGluR5 binding in a pilot study of late-life major depressive disorder using positron emission tomography and [¹¹C]ABP688 Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.Surface-based regional homogeneity in first-episode, drug-naïve major depression: a resting-state FMRI study High-field magnetic resonance imaging of structural alterations in first-episode, drug-naive patients with major depressive disorder.Investigational NMDA receptor modulators for depression.Neuroimaging markers of cellular function in major depressive disorder: implications for therapeutics, personalized medicine, and prevention.Radiosynthesis of carbon-11 and fluorine-18 labelled radiotracers to image the ionotropic and metabotropic glutamate receptors.Positron emission tomography molecular imaging in late-life depression.Imaging the pathophysiology of major depressive disorder - from localist models to circuit-based analysis.

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P2860

Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study.

http://www.wikidata.org/entity/Q35085729

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Reduced metabotropic glutamate ...... P688 PET and postmortem study.

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Reduced metabotropic glutamate ...... P688 PET and postmortem study.

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Anass Johayem

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P2860

Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum.

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats.

Architectonic subdivision of the human orbital and medial prefrontal cortex.

A diagnostic interview: the schedule for affective disorders and schizophrenia.

Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5.

Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice.

mGluR5 stimulates gliotransmission in the nucleus accumbens.

Consensus nomenclature for in vivo imaging of reversibly binding radioligands.

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