Natural genetic variation as a tool in understanding the role of CETP in lipid levels and disease.
about
Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressureAnacetrapib, a Novel CETP Inhibitor: Pursuing a New Approach to Cardiovascular Risk ReductionAPOE, CETP and LPL genes show strong association with lipid levels in Greek childrenSeparating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community.Cholesteryl ester transfer protein gene polymorphisms and longevity syndromeA genomewide search using an original pairwise sampling approach for large genealogies identifies a new locus for total and low-density lipoprotein cholesterol in two genetically differentiated isolates of Sardinia.Genetic causes of high and low serum HDL-cholesterol.High-density lipoprotein (HDL) particle subpopulations in heterozygous cholesteryl ester transfer protein (CETP) deficiency: maintenance of antioxidative activity.Cholesteryl ester transfer protein polymorphism (TaqIB) associates with risk in postinfarction patients with high C-reactive protein and high-density lipoprotein cholesterol levels.Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin.Cholesteryl ester transfer protein gene and effectiveness of lipid lowering of atorvastatin.Molecular regulation of HDL metabolism and function: implications for novel therapies.Alterations in high-density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and type 2 diabetes mellitus: role of lipolytic enzymes, lecithin:cholesterol acyltransferase and lipid transfer proteins.Genetic markers of cholesterol transport and gray matter diffusion: a preliminary study of the CETP I405V polymorphism.Resequencing of the CETP gene in American whites and African blacks: Association of rare and common variants with HDL-cholesterol levelsThe I405V and Taq1B polymorphisms of the CETP gene differentially affect sub-clinical carotid atherosclerosis.Effects of cholesterol ester transfer protein (CETP) gene on adiposity in response to long-term overfeedingGenetic variation in the OX40L/OX40 system and plasma lipid and lipoprotein levels in a Chinese hypertriglyceridemic population.CETP inhibition in cardiovascular risk management: a critical appraisal.The role of developing breast cancer in alteration of serum lipid profile.Cholesteryl ester transfer protein gene polymorphism (I405V) and premature coronary artery disease in an Iranian population.Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study.Future of cholesteryl ester transfer protein (CETP) inhibitors: a pharmacological perspective.Association of I405V polymorphism of colesteryl ester transfer protein gene with coronary artery disease in men with type 2 diabetesCommon variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis.Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.Elevated CETP Lipid Transfer Activity is Associated with the Risk of Venous Thromboembolism.Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction.Cholesteryl ester transfer protein inhibition in cardiovascular risk management: ongoing trials will end the confusion.On- and off-target pharmacology of torcetrapib: current understanding and implications for the structure activity relationships (SAR), discovery and development of cholesteryl ester-transfer protein (CETP) inhibitors.High-density lipoprotein in uremic patients: metabolism, impairment, and therapy.Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.Biochemical characterization of cholesteryl ester transfer protein inhibitorsTaqIB polymorphism in the cholesteryl ester transfer protein (CETP) gene influences lipid responses to the consumption of kiwifruit in hypercholesterolaemic men.Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS).5th Annual International Conference on HDL Cholesterol: metabolic pathways and drug developments.Effect of the cholesteryl ester transfer protein genotypes on plasma lipid and lipoprotein levels in Vietnamese children.Pharmacogenetic study of cholesteryl ester transfer protein gene and simvastatin treatment in hypercholesterolaemic subjects.
P2860
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P2860
Natural genetic variation as a tool in understanding the role of CETP in lipid levels and disease.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Natural genetic variation as a ...... P in lipid levels and disease.
@ast
Natural genetic variation as a ...... P in lipid levels and disease.
@en
type
label
Natural genetic variation as a ...... P in lipid levels and disease.
@ast
Natural genetic variation as a ...... P in lipid levels and disease.
@en
prefLabel
Natural genetic variation as a ...... P in lipid levels and disease.
@ast
Natural genetic variation as a ...... P in lipid levels and disease.
@en
P2860
P1476
Natural genetic variation as a ...... P in lipid levels and disease.
@en
P2093
John F Thompson
S Matthijs Boekholdt
P2860
P304
P356
10.1194/JLR.R200018-JLR200
P577
2003-03-16T00:00:00Z