Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.
about
Studying Cellular Signal Transduction with OMIC TechnologiesRecent findings and technological advances in phosphoproteomics for cells and tissuesLarge-scale label-free phosphoproteomics: from technology to data interpretation.A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells.Comprehensive characterization of (S)GTP-binding proteins by orthogonal quantitative (S)GTP-affinity profiling and (S)GTP/GTP competition assays.Phosphoproteomics for the massesPeptide reporters of kinase activity in whole cell lysates.Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotectionPhotocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MSSystematic analysis of the phosphoproteome and kinase-substrate networks in the mouse testis.Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.Phosphoproteomics in cancerProtein analysis by shotgun/bottom-up proteomicsPurification and identification of activating enzymes of CS-0777, a selective sphingosine 1-phosphate receptor 1 modulator, in erythrocytesKINATEST-ID: a pipeline to develop phosphorylation-dependent terbium sensitizing kinase assays.A miniaturized readout strategy for endogenous histone deacetylase activity.Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates.Multiplex Substrate Profiling by Mass Spectrometry for Kinases as a Method for Revealing Quantitative Substrate Motifs.Time-resolved luminescence detection of spleen tyrosine kinase activity through terbium sensitizationIdentification of a metabolizing enzyme in human kidney by proteomic correlation profiling.Signal transduction in cerebral arteries after subarachnoid hemorrhage-a phosphoproteomic approach.The revolution and evolution of shotgun proteomics for large-scale proteome analysis.Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples.Determining target engagement in living systemsBiological signalling activity measurements using mass spectrometry.Cancer proteomics.Analysing signalling networks by mass spectrometry.Measurement and modeling of signaling at the single-cell level.Peptide Arrays for Kinome Analysis of Livestock Species.The Peptide Microarray-Based Resonance Light Scattering Assay for Sensitively Detecting Intracellular Kinase Activity.Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways.Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance.Recent advances in methods to assess the activity of the kinome.Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.FLEXIQinase, a mass spectrometry-based assay, to unveil multikinase mechanisms.Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts.Evolution of protein phosphorylation across 18 fungal species.Application of targeted mass spectrometry in bottom-up proteomics for systems biology research.
P2860
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P2860
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Sensitive multiplexed analysis ...... y-based kinase identification.
@ast
Sensitive multiplexed analysis ...... y-based kinase identification.
@en
type
label
Sensitive multiplexed analysis ...... y-based kinase identification.
@ast
Sensitive multiplexed analysis ...... y-based kinase identification.
@en
prefLabel
Sensitive multiplexed analysis ...... y-based kinase identification.
@ast
Sensitive multiplexed analysis ...... y-based kinase identification.
@en
P2093
P2860
P50
P356
P1433
P1476
Sensitive multiplexed analysis ...... y-based kinase identification.
@en
P2093
Adam S Feldman
Chin-Lee Wu
Cloud Paweletz
Heike Keilhack
Kazuishi Kubota
Kumiko Nagashima
Manfred Kraus
Rana Anjum
Ronald C Hendrickson
P2860
P2888
P304
P356
10.1038/NBT.1566
P577
2009-10-04T00:00:00Z