BET bromodomain proteins are required for glioblastoma cell proliferation. - Wikidata - awgldk - TriplyDB

BET bromodomain proteins are required for glioblastoma cell proliferation.

BET bromodomain proteins are required for glioblastoma cell proliferation.

http://www.wikidata.org/entity/Q35086848

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Bromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System Tumors Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell Targeting Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery Targeting BET bromodomains for cancer treatment Registered report: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukemia BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma.BET proteins are a key component of immunoglobulin gene expression.Integrated genomic characterization of IDH1-mutant glioma malignant progression Emerging treatment strategies for glioblastoma multiforme The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.Identifying glioblastoma gene networks based on hypergeometric test analysis.The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation.Curcumin decreases malignant characteristics of glioblastoma stem cells via induction of reactive oxygen species.Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4.The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease An Insight into the Increasing Role of LncRNAs in the Pathogenesis of Gliomas.Epigenetic pathways and glioblastoma treatment: insights from signaling cascades.OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells.Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1 Bromodomain and extraterminal protein inhibitors in pediatrics: A review of the literature.Bromodomain inhibitors and cancer therapy: From structures to applications.Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.Long non-coding RNA in glioma: signaling pathways.Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine Glioma A Novel Epi-drug Therapy Based on the Suppression of BET Family Epigenetic Readers.Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations.Redox-Related Epigenetic Mechanisms in Glioblastoma: Nuclear Factor (Erythroid-Derived 2)-Like 2, Cobalamin, and Dopamine Receptor Subtype 4 Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4.M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.SPOP-mediated degradation of BRD4 dictates cellular sensitivity to BET inhibitors.Insights into the crystal structure of BRD2-BD2 - phenanthridinone complex and theoretical studies on phenanthridinone analogs.BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis.Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma.New Insights Into the Genomic Alterations in Glioma Progression.

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P2860

BET bromodomain proteins are required for glioblastoma cell proliferation.

http://www.wikidata.org/entity/Q35086848

description

2014 nî lūn-bûn

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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

BET bromodomain proteins are required for glioblastoma cell proliferation.

@ast

BET bromodomain proteins are required for glioblastoma cell proliferation.

@en

type

label

BET bromodomain proteins are required for glioblastoma cell proliferation.

@ast

BET bromodomain proteins are required for glioblastoma cell proliferation.

@en

prefLabel

BET bromodomain proteins are required for glioblastoma cell proliferation.

@ast

BET bromodomain proteins are required for glioblastoma cell proliferation.

@en

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P1476

BET bromodomain proteins are required for glioblastoma cell proliferation

@en

P2093

Andrea L Johnstone

http://www.w3.org/2001/XMLSchema#string

Chiara Pastori

http://www.w3.org/2001/XMLSchema#string

Claes Wahlestedt

http://www.w3.org/2001/XMLSchema#string

Jann N Sarkaria

http://www.w3.org/2001/XMLSchema#string

Mark Daniel

http://www.w3.org/2001/XMLSchema#string

Nagi G Ayad

http://www.w3.org/2001/XMLSchema#string

Ricardo J Komotar

http://www.w3.org/2001/XMLSchema#string

P2860

Epigenetic pathways and glioblastoma treatment

Selective inhibition of BET bromodomains

Suppression of inflammation by a synthetic histone mimic

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A)

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Direct multiplexed measurement of gene expression with color-coded probe pairs

Cancer epigenetics: from mechanism to therapy

P304

611-620

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scholarly article

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10.4161/EPI.27906

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4

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P478

9

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P50

Claude-Henry Volmar

Regina M Graham

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2014-02-19T00:00:00Z

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260094130

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24496381

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4121371

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