Plectin regulates the organization of glial fibrillary acidic protein in Alexander disease.
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Strategies for treatment in Alexander diseaseAlexander diseaseGFAP and its role in Alexander diseaseDysfunctions of neuronal and glial intermediate filaments in diseaseThe many faces of plectin and plectinopathies: pathology and mechanismsGenetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survivalPlectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migration.GFAP isoforms control intermediate filament network dynamics, cell morphology, and focal adhesions.The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander diseaseDrug screening to identify suppressors of GFAP expressionWithaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosisOligomers of mutant glial fibrillary acidic protein (GFAP) Inhibit the proteasome system in alexander disease astrocytes, and the small heat shock protein alphaB-crystallin reverses the inhibition.Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.Computational characterization of 3' splice variants in the GFAP isoform family.Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytesCSF and Blood Levels of GFAP in Alexander DiseaseBeneficial effects of Nrf2 overexpression in a mouse model of Alexander disease.Softness, strength and self-repair in intermediate filament networksGlial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-delta, but with consequences for filament organization and alphaB-crystallin association.Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander diseaseComposition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander DiseaseTargeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocityPlectin isoforms as organizers of intermediate filament cytoarchitecture.Plectin-intermediate filament partnership in skin, skeletal muscle, and peripheral nerve.Role of astrocytes in major neurological disorders: the evidence and implications.Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells.Astrocytes: a central element in neurological diseases.Glial fibrillary acidic protein exhibits altered turnover kinetics in a mouse model of Alexander disease.Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease.Alexander Disease Mutations Produce Cells with Coexpression of Glial Fibrillary Acidic Protein and NG2 in Neurosphere Cultures and Inhibit Differentiation into Mature OligodendrocytesProperties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice.Stabilization of the dystroglycan complex in Cajal bands of myelinating Schwann cells through plectin-mediated anchorage to vimentin filaments.
P2860
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P2860
Plectin regulates the organization of glial fibrillary acidic protein in Alexander disease.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
Plectin regulates the organiza ...... protein in Alexander disease.
@ast
Plectin regulates the organiza ...... protein in Alexander disease.
@en
type
label
Plectin regulates the organiza ...... protein in Alexander disease.
@ast
Plectin regulates the organiza ...... protein in Alexander disease.
@en
prefLabel
Plectin regulates the organiza ...... protein in Alexander disease.
@ast
Plectin regulates the organiza ...... protein in Alexander disease.
@en
P2093
P2860
P1476
Plectin regulates the organiza ...... protein in Alexander disease.
@en
P2093
James E Goldman
Martin Gregor
Rujin Tian
P2860
P304
P356
10.2353/AJPATH.2006.051028
P407
P577
2006-03-01T00:00:00Z