Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner.
about
In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin BRUG3 and ATM synergistically regulate the alternative splicing of mitochondrial nad2 and the DNA damage response in Arabidopsis thaliana.Epigallocatechin-3-gallate enhances the therapeutic effects of leptomycin B on human lung cancer a549 cells.An updated review of Cucurbitacins and their biological and pharmacological activities.PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells.Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E.Activation and Inhibition of ATM by Phytochemicals: Awakening and Sleeping the Guardian Angel Naturally.Inhibition of paclitaxel resistance and apoptosis induction by cucurbitacin B in ovarian carcinoma cells.Physalin A induces G2/M phase cell cycle arrest in human non-small cell lung cancer cells: involvement of the p38 MAPK/ROS pathway.Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549.Induction of ROS-independent DNA damage by curcumin leads to G2/M cell cycle arrest and apoptosis in human papillary thyroid carcinoma BCPAP cells.Hiporfin-mediated photodynamic therapy in preclinical treatment of osteosarcoma.Elaborating the role of natural products-induced autophagy in cancer treatment: achievements and artifacts in the state of the art.Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca2+ release in Leishmania mexicana promastigotes.Gold nanostars mediated combined photothermal and photodynamic therapy and X-ray imaging for cancer theranostic applications.Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells.Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in lymphoma Ramos cells.Camptothecin induces G2/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species.
P2860
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P2860
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner.
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2014 nî lūn-bûn
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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@ast
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@en
type
label
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@ast
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@en
prefLabel
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@ast
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@en
P2093
P2860
P1433
P1476
Cucurbitacin B induced ATM-med ...... est in a ROS-dependent manner.
@en
P2093
Guosheng Wu
Jiajie Guo
Jiaolin Bao
Wenhui Hao
Xiuping Chen
P2860
P304
P356
10.1371/JOURNAL.PONE.0088140
P407
P50
P577
2014-02-04T00:00:00Z