about
Activation of DNA Damage Response Induced by the Kaposi's Sarcoma-Associated Herpes VirusHuman Papillomavirus: Current and Future RNAi Therapeutic Strategies for Cervical CancerApplications of targeted proteomics in systems biology and translational medicineSenescence in adipose-derived stem cells and its implications in nerve regenerationHigh-throughput microfluidics to control and measure signaling dynamics in single yeast cells.Combinatorial gene regulation by modulation of relative pulse timing.Akt signaling dynamics in individual cells.Quantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryosCharacterizing the relationship between steady state and response using analytical expressions for the steady states of mass action modelsAccurate encoding and decoding by single cells: amplitude versus frequency modulationThe effects of interleukin-2 on immune response regulation.Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 inductionCircuit-level input integration in bacterial gene regulation.Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expressionGel2DE - a software tool for correlation analysis of 2D gel electrophoresis data.Stochastic sensitivity analysis and kernel inference via distributional data.Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cellsInterplay between Mdm2 and HIPK2 in the DNA damage response.Dynamics of posttranslational modifications of p53.p53 dynamics control cell fateMultifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenanceTension and robustness in multitasking cellular networks.Tunable signal processing through modular control of transcription factor translocation.Encoding and decoding cellular information through signaling dynamics.Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisionsNew insights into the link between DNA damage and apoptosis.Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damageMechanisms that enhance sustainability of p53 pulsesLevels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate.Constant rate of p53 tetramerization in response to DNA damage controls the p53 response.The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold.Computational analysis of signaling patterns in single cells.Medical Countermeasures for Radiation Exposure and Related Injuries: Characterization of Medicines, FDA-Approval Status and Inclusion into the Strategic National Stockpile.Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence SignallingLimits on information transduction through amplitude and frequency regulation of transcription factor activityOn the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer CellsThrough the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics.A novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanismsHow time delay and network design shape response patterns in biochemical negative feedback systems
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Stimulus-dependent dynamics of p53 in single cells.
@ast
Stimulus-dependent dynamics of p53 in single cells.
@en
type
label
Stimulus-dependent dynamics of p53 in single cells.
@ast
Stimulus-dependent dynamics of p53 in single cells.
@en
prefLabel
Stimulus-dependent dynamics of p53 in single cells.
@ast
Stimulus-dependent dynamics of p53 in single cells.
@en
P2093
P2860
P356
P1476
Stimulus-dependent dynamics of p53 in single cells.
@en
P2093
Alexander Loewer
Caroline Mock
Eric Batchelor
Galit Lahav
P2860
P356
10.1038/MSB.2011.20
P577
2011-05-01T00:00:00Z