Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates.
about
Spore photoproduct lyase: the known, the controversial, and the unknownStructural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzymeA Radical Transfer Pathway in Spore Photoproduct LyaseRescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyaseInsights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine ResidueUnusually large deuterium discrimination during spore photoproduct formation.Combined Mössbauer spectroscopic, multi-edge X-ray absorption spectroscopic, and density functional theoretical study of the radical SAM enzyme spore photoproduct lyase.Recent advances in radical SAM enzymology: new structures and mechanisms.Insight in DNA Repair of UV-induced Pyrimidine Dimers by Chromatographic Methods.Chemical synthesis, crystal structure and enzymatic evaluation of a dinucleotide spore photoproduct analogue containing a formacetal linkerAirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus.Mechanistic studies of the radical SAM enzyme spore photoproduct lyase (SPL).Photochemistry and Photobiology of the Spore Photoproduct: A 50-Year Journey.Mechanistic studies of the spore photoproduct lyase via a single cysteine mutationCovalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.Chemical syntheses of oligodeoxyribonucleotides containing spore photoproduct.The enzyme-mediated direct reversal of a dithymine photoproduct in germinating endosporesRadical S-adenosylmethionine enzymes.Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions.Spore photoproduct within DNA is a surprisingly poor substrate for its designated repair enzyme-The spore photoproduct lyase.DNA Repair by the Radical SAM Enzyme Spore Photoproduct Lyase: From Biochemistry to Structural Investigations.Hydrogen transfer in SAM-mediated enzymatic radical reactions.Direct observation of a deoxyadenosyl radical in an active enzyme environment.Kinetic Isotope Effects and Hydrogen/Deuterium Exchange Reveal Large Conformational Changes During the Catalysis of the Clostridium acetobutylicum Spore Photoproduct Lyase.The radical SAM enzyme spore photoproduct lyase employs a tyrosyl radical for DNA repair
P2860
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P2860
Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Probing the reaction mechanism ...... inucleotide SP TpT substrates.
@ast
Probing the reaction mechanism ...... inucleotide SP TpT substrates.
@en
type
label
Probing the reaction mechanism ...... inucleotide SP TpT substrates.
@ast
Probing the reaction mechanism ...... inucleotide SP TpT substrates.
@en
prefLabel
Probing the reaction mechanism ...... inucleotide SP TpT substrates.
@ast
Probing the reaction mechanism ...... inucleotide SP TpT substrates.
@en
P2093
P2860
P356
P1476
Probing the reaction mechanism ...... dinucleotide SP TpT substrates
@en
P2093
Degang Liu
Gengjie Lin
Karl J Dria
Linlin Yang
P2860
P304
10434-10447
P356
10.1021/JA110196D
P407
P577
2011-06-14T00:00:00Z