TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study.
about
Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusToll-like receptors in systemic lupus erythematosus: potential targets for therapeutic interventionB cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody productionIntracellular nucleic acid sensors and autoimmunityImmunological function of Blimp-1 in dendritic cells and relevance to autoimmune diseasesTargeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signalingSpontaneous activation of RNA-sensing pathways in autoimmune disease.Altered B cell signalling in autoimmunity.Activation of type I interferon pathway in systemic lupus erythematosus: association with distinct clinical phenotypes.Toll-like receptor 7 stimulates the expression of Epstein-Barr virus latent membrane protein 1MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus.Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritisNegative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.Genetics of SLE: functional relevance for monocytes/macrophages in diseaseB-cell selection and the development of autoantibodies.B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice.Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's diseaseScavenging nucleic acid debris to combat autoimmunity and infectious disease.Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population.TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 miceKruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele.TLR7 and TLR9 in SLE: when sensing self goes wrong.The genetics of innate immunity sensors and human disease.Toll-like receptors and B cells: functions and mechanisms.Toll-like receptor 7 gene single nucleotide polymorphisms and the risk for systemic lupus erythematosus: a case-control study.Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity.The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling.Deficiency in IRAK4 activity attenuates manifestations of murine Lupus.Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update.Toll like receptor7 polymorphisms in relation to disease susceptibility and progression in Chinese patients with chronic HBV infection.IFN-β therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients.Enhanced IFN-α production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosusPolymorphisms within Toll-like receptors are associated with systemic lupus erythematosus in a cohort of Danish females.Predictive value of TLR7 polymorphism for cetuximab-based chemotherapy in patients with metastatic colorectal cancer.Association of a single nucleotide polymorphism in the SH2D1A intronic region with systemic lupus erythematosus.TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from southern Brazil.Toll-like receptors in lupus nephritis.X-linked TLR7 gene polymorphisms are associated with diverse immunological conditions but not with discoid lupus erythematosus in Polish patients.
P2860
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P2860
TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
TLR7 single-nucleotide polymor ...... ase-control association study.
@ast
TLR7 single-nucleotide polymor ...... ase-control association study.
@en
type
label
TLR7 single-nucleotide polymor ...... ase-control association study.
@ast
TLR7 single-nucleotide polymor ...... ase-control association study.
@en
prefLabel
TLR7 single-nucleotide polymor ...... ase-control association study.
@ast
TLR7 single-nucleotide polymor ...... ase-control association study.
@en
P2093
P2860
P356
P1476
TLR7 single-nucleotide polymor ...... case-control association study
@en
P2093
Aya Kawasaki
Hiroshi Furukawa
Hiroshi Hashimoto
Isao Matsumoto
Makio Kusaoi
Satoshi Ito
Shigeto Tohma
Taichi Hayashi
Takayuki Sumida
Yoshinari Takasaki
P2860
P2888
P356
10.1186/AR3277
P577
2011-03-11T00:00:00Z