FAT10 modifies p53 and upregulates its transcriptional activity. - Wikidata - awgldk - TriplyDB

FAT10 modifies p53 and upregulates its transcriptional activity.

FAT10 modifies p53 and upregulates its transcriptional activity.

http://www.wikidata.org/entity/Q35097418

about

Modification by ubiquitin-like proteins: significance in apoptosis and autophagy pathways Disruption of FAT10-MAD2 binding inhibits tumor progression.Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6 Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity.FAT10 protects cardiac myocytes against apoptosis.Profiling of ubiquitin-like modifications reveals features of mitotic control.FAT10 is associated with the malignancy and drug resistance of non-small-cell lung cancer Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease?Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.HIV-1, ubiquitin and ubiquitin-like proteins: the dialectic interactions of a virus with a sophisticated network of post-translational modifications.FAT10 protein binds to polyglutamine proteins and modulates their solubility.NFκB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53.FAT10, an ubiquitin-like protein, confers malignant properties in non-tumorigenic and tumorigenic cells.Increased expression of FAT10 is correlated with progression and prognosis of human glioma.Upregulation of p-Smad2 contributes to FAT10-induced oncogenic activities in glioma.

P2860

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P2860

FAT10 modifies p53 and upregulates its transcriptional activity.

http://www.wikidata.org/entity/Q35097418

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մարտին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

FAT10 modifies p53 and upregulates its transcriptional activity.

@ast

FAT10 modifies p53 and upregulates its transcriptional activity.

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type

label

FAT10 modifies p53 and upregulates its transcriptional activity.

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FAT10 modifies p53 and upregulates its transcriptional activity.

@en

prefLabel

FAT10 modifies p53 and upregulates its transcriptional activity.

@ast

FAT10 modifies p53 and upregulates its transcriptional activity.

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J.ABB.2011.02.017

P1433

Archives of Biochemistry and Biophysics

P1476

FAT10 modifies p53 and upregulates its transcriptional activity.

@en

P2093

Caroline G L Lee

http://www.w3.org/2001/XMLSchema#string

David C H Yang

http://www.w3.org/2001/XMLSchema#string

Ephrem Tekle

http://www.w3.org/2001/XMLSchema#string

P Boon Chock

http://www.w3.org/2001/XMLSchema#string

Rasa Santockyte

http://www.w3.org/2001/XMLSchema#string

Rong-Fong Shen

http://www.w3.org/2001/XMLSchema#string

Shiqin Yu

http://www.w3.org/2001/XMLSchema#string

Tianwei Li

http://www.w3.org/2001/XMLSchema#string

P2860

A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Regulation of p53 activity in nuclear bodies by a specific PML isoform

E1-L2 activates both ubiquitin and FAT10

FAT10, a ubiquitin-independent signal for proteasomal degradation

Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers

FAT10 plays a role in the regulation of chromosomal stability

NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation

The ubiquitin-like protein FAT10 mediates NF-kappaB activation

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

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164-169

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scholarly article

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10.1016/J.ABB.2011.02.017

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2

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509

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2011-03-09T00:00:00Z

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50374558

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21396347

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3133660

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