FAT10 modifies p53 and upregulates its transcriptional activity.
about
Modification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysDisruption of FAT10-MAD2 binding inhibits tumor progression.Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity.FAT10 protects cardiac myocytes against apoptosis.Profiling of ubiquitin-like modifications reveals features of mitotic control.FAT10 is associated with the malignancy and drug resistance of non-small-cell lung cancerNodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease?Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.HIV-1, ubiquitin and ubiquitin-like proteins: the dialectic interactions of a virus with a sophisticated network of post-translational modifications.FAT10 protein binds to polyglutamine proteins and modulates their solubility.NFκB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53.FAT10, an ubiquitin-like protein, confers malignant properties in non-tumorigenic and tumorigenic cells.Increased expression of FAT10 is correlated with progression and prognosis of human glioma.Upregulation of p-Smad2 contributes to FAT10-induced oncogenic activities in glioma.
P2860
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P2860
FAT10 modifies p53 and upregulates its transcriptional activity.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
FAT10 modifies p53 and upregulates its transcriptional activity.
@ast
FAT10 modifies p53 and upregulates its transcriptional activity.
@en
type
label
FAT10 modifies p53 and upregulates its transcriptional activity.
@ast
FAT10 modifies p53 and upregulates its transcriptional activity.
@en
prefLabel
FAT10 modifies p53 and upregulates its transcriptional activity.
@ast
FAT10 modifies p53 and upregulates its transcriptional activity.
@en
P2093
P2860
P1476
FAT10 modifies p53 and upregulates its transcriptional activity.
@en
P2093
Caroline G L Lee
David C H Yang
Ephrem Tekle
P Boon Chock
Rasa Santockyte
Rong-Fong Shen
Tianwei Li
P2860
P304
P356
10.1016/J.ABB.2011.02.017
P407
P577
2011-03-09T00:00:00Z