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Feedback amplification of fibrosis through matrix stiffening and COX-2 suppressionAltered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosisOverexpression of cathepsin K during silica-induced lung fibrosis and control by TGF-beta.Wnt signalling in lung development and diseasesThe Elusive Antifibrotic MacrophageAlways cleave up your mess: targeting collagen degradation to treat tissue fibrosisGene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesisCathepsin K inhibitors for osteoporosis and potential off-target effectsRegulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.Characterization of proteolytic activities during intestinal regeneration of the sea cucumber, Holothuria glaberrima.MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets.Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models.Scleroderma: from pathophysiology to novel therapeutic approaches.Role for cathepsin K in emphysema in smoke-exposed guinea pigsThe effect of cathepsin K deficiency on airway development and TGF-β1 degradation.Multiplex zymography captures stage-specific activity profiles of cathepsins K, L, and S in human breast, lung, and cervical cancerRemodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk.Ultraviolet A-induced cathepsin K expression is mediated via MAPK/AP-1 pathway in human dermal fibroblasts.Mannose receptor 2 attenuates renal fibrosisTranscriptome Reveals Cathepsin K in Periodontal Ligament Differentiation.Potential role of odanacatib in the treatment of osteoporosis.Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling.TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.Cysteine cathepsins and caspases in silicosis.Cysteine cathepsins: regulators of antitumour immune response.Nuclear cathepsin F regulates activation markers in rat hepatic stellate cellsSecretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression.Functional genomic screen identifies novel mediators of collagen uptake.A broad survey of cathepsin K immunoreactivity in human neoplasms.Specialized roles for cysteine cathepsins in health and disease.Odanacatib for the treatment of osteoporosis.Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases.Cathepsin K osteoporosis trials, pycnodysostosis and mouse deficiency models: Commonalities and differences.Engineered nanomaterial-induced lysosomal membrane permeabilization and anti-cathepsin agents.Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms.Radiation-induced matrix production of lung fibroblasts is regulated by interleukin-8.Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts.Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Pivotal role of cathepsin K in lung fibrosis.
@ast
Pivotal role of cathepsin K in lung fibrosis.
@en
type
label
Pivotal role of cathepsin K in lung fibrosis.
@ast
Pivotal role of cathepsin K in lung fibrosis.
@en
prefLabel
Pivotal role of cathepsin K in lung fibrosis.
@ast
Pivotal role of cathepsin K in lung fibrosis.
@en
P2093
P2860
P1476
Pivotal role of cathepsin K in lung fibrosis.
@en
P2093
Christoph Röcken
Dieter Brömme
Frank Brasch
Frank Bühling
Paul Saftig
Roland Hartig
Yoshiyuki Yasuda
P2860
P304
P356
10.1016/S0002-9440(10)63777-7
P407
P50
P577
2004-06-01T00:00:00Z