[32P]2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([32P]MRS2500), a novel radioligand for quantification of native P2Y1 receptors.
about
Development of selective agonists and antagonists of P2Y receptors.Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells.Pharmacochemistry of the platelet purinergic receptors.Functionalized congeners of P2Y1 receptor antagonists: 2-alkynyl (N)-methanocarba 2'-deoxyadenosine 3',5'-bisphosphate analogues and conjugation to a polyamidoamine (PAMAM) dendrimer carrier.UDP is a competitive antagonist at the human P2Y14 receptorP2Y nucleotide receptors: promise of therapeutic applicationsSer352 and Ser354 in the carboxyl terminus of the human P2Y(1) receptor are required for agonist-promoted phosphorylation and internalization in MDCK cellsDevelopment of selective high affinity antagonists, agonists, and radioligands for the P2Y1 receptor.Agonists and antagonists for P2 receptors.The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening(N)-methanocarba-2MeSADP (MRS2365) is a subtype-specific agonist that induces rapid desensitization of the P2Y1 receptor of human platelets.Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([(125)I]MRS2500)Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors.Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotidesStimulation of the P2Y1 receptor up-regulates nucleoside-triphosphate diphosphohydrolase-1 in human retinal pigment epithelial cells.Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology.The platelet P2Y(12) receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [(3)H]PSB-0413.Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation.Microglia P2Y13 Receptors Prevent Astrocyte Proliferation Mediated by P2Y1 Receptors.
P2860
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P2860
[32P]2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([32P]MRS2500), a novel radioligand for quantification of native P2Y1 receptors.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@ast
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@en
type
label
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@ast
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@en
prefLabel
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@ast
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@en
P2093
P2860
P356
P1476
[32P]2-iodo-N6-methyl-(N)-meth ...... tion of native P2Y1 receptors.
@en
P2093
Dayle Houston
Kenneth A Jacobson
Michihiro Ohno
Robert A Nicholas
T Kendall Harden
P2860
P304
P356
10.1038/SJ.BJP.0706453
P407
P577
2006-03-01T00:00:00Z