Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors - Wikidata - awgldk - TriplyDB

Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

http://www.wikidata.org/entity/Q35100928

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ARMC5 mutations in macronodular adrenal hyperplasia with Cushing's syndrome Alterations of Phosphodiesterases in Adrenocortical Tumors ACTH-independent Cushing's syndrome with bilateral micronodular adrenal hyperplasia and ectopic adrenocortical adenoma.Cyclic AMP, protein kinase A, and phosphodiesterases: proceedings of an international workshop Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype.Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer.Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma.Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes.p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation.Phosphodiesterase sequence variants may predispose to prostate cancer.Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours.Protein kinase A defects and cortisol-producing adrenal tumors Regulation of the adrenocortical stem cell niche: implications for disease Phosphodiesterase 11A (PDE11A) gene defects in patients with acth-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse.New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors.The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.Genetic variation in phosphodiesterase (PDE) 7B in chronic lymphocytic leukemia: overview of genetic variants of cyclic nucleotide PDEs in human disease.Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors.Targeting cancer with phosphodiesterase inhibitors.Clinical and molecular genetics of the phosphodiesterases (PDEs).Genetic aspects of adrenocortical tumours and hyperplasias.A genetic and molecular update on adrenocortical causes of Cushing syndrome.E pluribus unum? The main protein kinase A catalytic subunit (PRKACA), a likely oncogene, and cortisol-producing tumors.A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood.Activating PRKACB somatic mutation in cortisol-producing adenomas.The Many Faces of Primary Aldosteronism and Cushing Syndrome: A Reflection of Adrenocortical Tumor Heterogeneity.

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P2860

Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

http://www.wikidata.org/entity/Q35100928

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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type

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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1078-0432.CCR-08-0106

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Clinical Cancer Research

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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P2093

Amato Fratticci

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Anelia Horvath

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Fernande Rene-Corail

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Frédérique Tissier

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Joel Coste

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Marie Laure Raffin-Sanson

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Xavier Bertagna

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P2860

Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

Impaired desensitization of a mutant adrenocorticotropin receptor associated with apparent constitutive activity

A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

Familial cancer associated with a polymorphism in ARLTS1

Phosphodiesterases in the CNS: targets for drug development

Association between common variation in 120 candidate genes and breast cancer risk.

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

Activating mutations of the stimulatory G protein in the McCune-Albright syndrome.

Adrenocortical cancer: recent clinical and molecular advances.

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4016-4024

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10.1158/1078-0432.CCR-08-0106

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12

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14

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Lionel Groussin

Jérome Bertherat

Constantine A Stratakis

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2008-06-01T00:00:00Z

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5296360

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3134879

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