Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses. - Wikidata - awgldk - TriplyDB

Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.

Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.

http://www.wikidata.org/entity/Q35101324

about

Brd4-independent transcriptional repression function of the papillomavirus e2 proteins Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription A Structural Basis for BRD2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus LANA Proteins The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins Viral Genome Tethering to Host Cell Chromatin: Cause and Consequences The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle BET domain co-regulators in obesity, inflammation and cancer Analysis of the papillomavirus E2 and bromodomain protein Brd4 interaction using bimolecular fluorescence complementation Phosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomes Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment.Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression Papillomavirus interaction with cellular chromatin.Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.The cellular bromodomain protein Brd4 has multiple functions in E2-mediated papillomavirus transcription activation Recruitment of Brd4 to the human papillomavirus type 16 DNA replication complex is essential for replication of viral DNA.Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Small molecule inhibitors of human papillomavirus protein - protein interactions.Replication and partitioning of papillomavirus genomes.Evolutionary variation of papillomavirus E2 protein and E2 binding sites.RAP1 GTPase overexpression is associated with cervical intraepithelial neoplasia.Identification and analysis of papillomavirus E2 protein binding sites in the human genome.A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence.Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency.Replication and assembly of human papillomaviruses.Productive Lifecycle of Human Papillomaviruses that Depends Upon Squamous Epithelial Differentiation.A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groups BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency Recent advances in the search for antiviral agents against human papillomaviruses.An interaction between human papillomavirus 16 E2 and TopBP1 is required for optimum viral DNA replication and episomal genome establishment Proteomic approaches to the study of papillomavirus-host interactions.Dimerization of the papillomavirus E2 protein is required for efficient mitotic chromosome association and Brd4 binding.Failure to interact with Brd4 alters the ability of HPV16 E2 to regulate host genome expression and cellular movement The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4 Current understanding of the role of the Brd4 protein in the papillomavirus lifecycle.DNA Damage Reduces the Quality, but Not the Quantity of Human Papillomavirus 16 E1 and E2 DNA Replication Chromatin organization and virus gene expression.

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P2860

Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.

http://www.wikidata.org/entity/Q35101324

description

2006 nî lūn-bûn

@nan

2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

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Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

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type

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Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

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Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

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Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

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Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

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P1433

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P1433

Journal of Virology

P1476

Brd4 is required for e2-mediat ...... oning of all papillomaviruses.

@en

P2093

J E Spindler

http://www.w3.org/2001/XMLSchema#string

J G Oliveira

http://www.w3.org/2001/XMLSchema#string

M G McPhillips

http://www.w3.org/2001/XMLSchema#string

R Mitra

http://www.w3.org/2001/XMLSchema#string

P2860

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

Cooperative activation of human papillomavirus type 8 gene expression by the E2 protein and the cellular coactivator p300.

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4.

A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

P304

9530-9543

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scholarly article

P356

10.1128/JVI.01105-06

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P407

P433

19

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P478

80

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P50

Alison A. McBride

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2006-10-01T00:00:00Z

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P5875

6816936

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16973557

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P932

1617221

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