Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology - Wikidata - awgldk - TriplyDB

Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology

Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology

http://www.wikidata.org/entity/Q35103283

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Novel siRNA delivery system to target podocytes in vivo Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease CDK inhibitor p21 is prosurvival in adriamycin-induced podocyte injury, in vitro and in vivo.Daily Intake of Grape Powder Prevents the Progression of Kidney Disease in Obese Type 2 Diabetic ZSF1 Rats Both cyclin I and p35 are required for maximal survival benefit of cyclin-dependent kinase 5 in kidney podocytes.Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression Expression of CCN1 (CYR61) in developing, normal, and diseased human kidney.Cyclin I and p35 determine the subcellular distribution of Cdk5.RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5.ACE-inhibition increases podocyte number in experimental glomerular disease independent of proliferation.Valproic acid attenuates proteinuria and kidney injury.Podocyte Number in Children and Adults: Associations with Glomerular Size and Numbers of Other Glomerular Resident Cells PKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motility Cell cycle re-entry sensitizes podocytes to injury induced death.Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis Extraneuronal roles of cyclin-dependent kinase 5.The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells.CDK5 promotes renal tubulointerstitial fibrosis in diabetic nephropathy via ERK1/2/PPARγ pathway Papp-Lantos inclusions and the pathogenesis of multiple system atrophy: an update.Human kidney cell reprogramming: applications for disease modeling and personalized medicine Multiple system atrophy: genetic or epigenetic?Developmental changes of BKCa channels depend on differentiation status in cultured podocytes.Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease.Mechanical strain increases SPARC levels in podocytes: implications for glomerulosclerosis.Nestin protects mouse podocytes against high glucose-induced apoptosis by a Cdk5-dependent mechanism.The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics.Cell cycle regulatory proteins in podocyte health and disease.Cell cycle and glomerular disease: a minireview.A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

P2860

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P2860

Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology

http://www.wikidata.org/entity/Q35103283

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2004 nî lūn-bûn

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2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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Cyclin-dependent kinase 5 is a ...... proliferation, and morphology

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The American Journal of Pathology

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Cyclin-dependent kinase 5 is a ...... proliferation, and morphology

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P2093

Arndt T Petermann

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Ashok B Kulkarni

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Jeffrey Pippin

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Keiju Hiromura

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Mary J Blonski

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Ron Krofft

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Satoru Takahashi

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Sian V Griffin

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Stuart J Shankland

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P2860

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Expression of the neuronal cyclin-dependent kinase 5 activator p35Nck5a in human monocytic cells is associated with differentiation

Cyclin dependent kinase 5, cdk5, is a positive regulator of myogenesis in mouse C2 cells

Podocyte expression of the CDK-inhibitor p57 during development and disease

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

Cyclin-dependent kinase 5 is associated with apoptotic cell death during development and tissue remodeling

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

A decade of CDK5.

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1175-1185

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8250034

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15466384

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1618643

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