Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology
about
Novel siRNA delivery system to target podocytes in vivoPhosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney developmentGlutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activityCells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular diseaseCDK inhibitor p21 is prosurvival in adriamycin-induced podocyte injury, in vitro and in vivo.Daily Intake of Grape Powder Prevents the Progression of Kidney Disease in Obese Type 2 Diabetic ZSF1 RatsBoth cyclin I and p35 are required for maximal survival benefit of cyclin-dependent kinase 5 in kidney podocytes.Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expressionExpression of CCN1 (CYR61) in developing, normal, and diseased human kidney.Cyclin I and p35 determine the subcellular distribution of Cdk5.RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5.ACE-inhibition increases podocyte number in experimental glomerular disease independent of proliferation.Valproic acid attenuates proteinuria and kidney injury.Podocyte Number in Children and Adults: Associations with Glomerular Size and Numbers of Other Glomerular Resident CellsPKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motilityCell cycle re-entry sensitizes podocytes to injury induced death.Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte ApoptosisExtraneuronal roles of cyclin-dependent kinase 5.The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells.CDK5 promotes renal tubulointerstitial fibrosis in diabetic nephropathy via ERK1/2/PPARγ pathwayPapp-Lantos inclusions and the pathogenesis of multiple system atrophy: an update.Human kidney cell reprogramming: applications for disease modeling and personalized medicineMultiple system atrophy: genetic or epigenetic?Developmental changes of BKCa channels depend on differentiation status in cultured podocytes.Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease.Mechanical strain increases SPARC levels in podocytes: implications for glomerulosclerosis.Nestin protects mouse podocytes against high glucose-induced apoptosis by a Cdk5-dependent mechanism.The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics.Cell cycle regulatory proteins in podocyte health and disease.Cell cycle and glomerular disease: a minireview.A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.
P2860
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P2860
Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@ast
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@en
type
label
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@ast
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@en
prefLabel
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@ast
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@en
P2093
P2860
P1476
Cyclin-dependent kinase 5 is a ...... proliferation, and morphology
@en
P2093
Arndt T Petermann
Ashok B Kulkarni
Jeffrey Pippin
Keiju Hiromura
Mary J Blonski
Ron Krofft
Satoru Takahashi
Sian V Griffin
Stuart J Shankland
P2860
P304
P356
10.1016/S0002-9440(10)63378-0
P407
P577
2004-10-01T00:00:00Z