Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1) - Wikidata - awgldk - TriplyDB

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

http://www.wikidata.org/entity/Q33843707

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Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cells Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion Novel siRNA delivery system to target podocytes in vivo Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy Cloning and functional expression of a degradation-resistant novel isoform of p27Kip1 Protective function of p27(KIP1) against apoptosis in small cell lung cancer cells in unfavorable microenvironments High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-dependent kinases Characterization of cyclin E expression in multiple myeloma and its functional role in seliciclib-induced apoptotic cell death cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells Angiotensin II's antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20 Cyclooxygenase-2 overexpression inhibits platelet-derived growth factor-induced mesangial cell proliferation through induction of the tumor suppressor gene p53 and the cyclin-dependent kinase inhibitors p21waf-1/cip-1 and p27kip-1 Altered prostatic epithelial proliferation and apoptosis, prostatic development, and serum testosterone in mice lacking cyclin-dependent kinase inhibitors The rapamycin derivative RAD inhibits mesangial cell migration through the CDK-inhibitor p27KIP1.CDK inhibitor p21 is prosurvival in adriamycin-induced podocyte injury, in vitro and in vivo.G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression.Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.Cell cycle regulatory proteins in renal disease: role in hypertrophy, proliferation, and apoptosis.ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress.Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2 Cell cycle and apoptosis.Apoptosis and liver diseases: recent concepts of mechanism and significance.The Role of SIRT1 in Diabetic Kidney Disease.Activity of the heat shock protein 90 inhibitor ganetespib in melanoma Both cyclin I and p35 are required for maximal survival benefit of cyclin-dependent kinase 5 in kidney podocytes.Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways.Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology P27kip1 regulates the apoptotic response of gastric epithelial cells to Helicobacter pylori.Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach.Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1.Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak.Mimicking Cdk2 phosphorylation of Bcl-xL at Ser73 results in caspase activation and Bcl-xL cleavage.Differential regulation of cyclin-dependent kinase inhibitors in neuroblastoma cells Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension.Iroquois homeobox transcription factor (Irx5) promotes G1/S-phase transition in vascular smooth muscle cells by CDK2-dependent activation Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo.p27kip1: a new multiple endocrine neoplasia gene?Targeting p27Kip1 protein: its relevance in the therapy of human cancer.The role of the ubiquitin-proteasome system in kidney diseases.p27 and leukemia: cell cycle and beyond.

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P2860

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

http://www.wikidata.org/entity/Q33843707

description

1999 nî lūn-bûn

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1999 թուականի Մարտին հրատարակուած գիտական յօդուած

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1999 թվականի մարտին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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type

label

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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prefLabel

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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Journal of Clinical Investigation

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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

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P2093

J M Roberts

http://www.w3.org/2001/XMLSchema#string

J W Pippin

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K Hiromura

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M L Fero

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S J Shankland

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P2860

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells

Apoptosis in the pathogenesis and treatment of disease

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

Inhibitors of mammalian G1 cyclin-dependent kinases

Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2 caspase, and cyclin-dependent kinase activities.

Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation.

Mesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis

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10.1172/JCI5461

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10074476

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408127

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