PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42 - Wikidata - awgldk - TriplyDB

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

http://www.wikidata.org/entity/Q35107387

about

Lipid peroxidation and its toxicological implications Future technology insight: mass spectrometry imaging as a tool in drug research and development.Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids Abeta mediated diminution of MTT reduction--an artefact of single cell culture?Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice.Characterization of scavengers of gamma-ketoaldehydes that do not inhibit prostaglandin biosynthesis.On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry Determination of 3-methoxysalicylamine levels in mouse plasma and tissue by liquid chromatography-tandem mass spectrometry: application to in vivo pharmacokinetics studies Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.A new mechanism links preamyloid oligomer formation in the myocyte stress response associated with atrial fibrillation.Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS.The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.Isoprostane generation and function.Isolevuglandin adducts in disease Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts.Formation of gamma-ketoaldehyde-protein adducts during ethanol-induced liver injury in mice.Soluble state high resolution atomic force microscopy study of Alzheimer's beta-amyloid oligomers.Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.Molecular Structures of Isolevuglandin-Protein Cross-Links.Total Synthesis Confirms the Molecular Structure Proposed for Oxidized Levuglandin D2.

P2860

Q27691302-22C11DD2-465A-4ADE-994A-E86A6FF51309 Q28087460-F8253CAD-2D88-4616-A5C8-F3BA4CF5E6DC Q28389004-386DD06B-A673-4DCC-BA9D-BD3FF1C697FC Q28473625-00D37D5C-9DC2-445A-A6D8-761B06840A42 Q30505920-80DAB424-D344-4C82-9036-25A48F0B13A9 Q33701495-561D0C7A-33C3-4F93-96B6-E44690FE4651 Q33990585-65080B23-DBD7-491C-8A86-C88AF5F36A29 Q34965048-57901ACF-D148-49A2-B80B-0EEA5DF517AF Q34995740-19A67DA0-D831-4AC1-8C9C-BA796B108E2D Q35126030-7B38F6B7-D3D9-40D5-8DA2-438391D61B4C Q35137541-0A43D21B-A59A-4B66-B575-CBC76E773ADF Q35148031-333A4366-4275-4502-A425-0260E92F1E83 Q35327219-B453C4C1-B326-4341-8D07-E2EA81E24F93 Q35332267-2B2E0455-913B-479B-8E10-90A7222710A3 Q35794678-E77A8B94-D275-464B-A101-531E0B528EAC Q37438010-7FB8B6FC-CA9C-4FF4-BA3A-3099FBC80386 Q37438265-99EBE3D2-BAF0-4005-AC1A-4C5D51F2ED36 Q37460809-15972291-E50A-49E0-AA7B-5CDCCB0E675D Q37717636-7FB5D0F4-265A-40F8-B21D-D491C2B1519F Q37724402-890AF9F2-7581-44A6-822F-F8DC6365B69D Q42214486-58BBB494-B312-4215-9294-BC03953C3E14 Q48239770-D57D3386-086A-4A6C-990C-5D5EB525DF13

P2860

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

http://www.wikidata.org/entity/Q35107387

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@ast

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@en

type

label

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@ast

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@en

prefLabel

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@ast

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@en

P1433

Q35107387-C999F95D-61B6-4D39-A242-B47F590F1C38

P1476

Q35107387-F33CB8AC-F8DC-4CE6-A59F-97D47737E796

P2093

Q35107387-16471F59-B18C-4154-A907-F6B055F19710

Q35107387-6B796D6B-61C7-490B-B5D6-D079B0CCB77A

Q35107387-783E844B-82C2-46FC-BF7B-A04E0EEB7478

Q35107387-80039FD5-87BF-4BEB-A146-AEEC687DD79B

Q35107387-91DFDD59-37F1-427E-B447-62AE9E4AE6A3

P2860

Q35107387-11053CCC-FE8D-4FF5-ADC6-A5FD4B76902E

Q35107387-13E246F2-BC90-4AC3-92EF-6E8773CE5B11

Q35107387-142A576F-A1F4-4218-B53C-E00B94CBB319

Q35107387-19386F67-5BFA-4705-B6BC-C0764365CFEB

Q35107387-22C58211-C39D-4F4D-92C8-5A82AF3D34AE

Q35107387-291B0048-27D2-4F02-AC86-21E742CC2887

Q35107387-2E381B3F-2235-4E3C-8614-FE0EFFC731E3

Q35107387-301B4B29-C6F8-4E38-A3A9-E84BBDA7F538

Q35107387-309DDDA3-464B-4DA7-8236-06F4BB36240F

Q35107387-377CC783-8526-42FF-9875-FC4F700F935A

P304

Q35107387-6ECC9DA8-CA63-4E00-94F5-E9DAF81ACC65

P31

Q35107387-837E3C04-5D50-48FF-B68A-EDE90A1DE065

P356

Q35107387-F5D9FBDE-94B6-4DB3-8E99-E581BEEDA08E

P407

Q35107387-48644E43-569A-42AE-A25D-0E4435DB5174

P433

Q35107387-50EA8AEE-A071-467C-BED7-31C827988684

P478

Q35107387-FCA8CA54-D309-4727-8165-5A5F09CB297A

P577

Q35107387-6D9AD3D3-2615-445C-9A25-41CD7310484C

P5875

Q35107387-0EAB64D8-0A23-4D9F-8273-4648A1D5545A

P698

Q35107387-0C2EC329-6D09-4B30-BFBB-02B096EFB85B

P921

Q35107387-CD138A24-C2B4-41E4-A590-31426AD624B5

P932

Q35107387-4193D96B-87F0-40DF-9FE8-D8E4455E270C

P356

J.1471-4159.2005.03586.X

P1433

Journal of Neurochemistry

P1476

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

@en

P2093

John A Oates

http://www.w3.org/2001/XMLSchema#string

Lei Chang

http://www.w3.org/2001/XMLSchema#string

Olivier Boutaud

http://www.w3.org/2001/XMLSchema#string

Thomas J Montine

http://www.w3.org/2001/XMLSchema#string

William L Klein

http://www.w3.org/2001/XMLSchema#string

P2860

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Characterization of the lysyl adducts formed from prostaglandin H2 via the levuglandin pathway

Prostaglandin endoperoxides. 14. Solvent-induced fragmentation of prostaglandin endoperoxides. New aldehyde products from PGH2 and a novel intramolecular 1,2-hydride shift during endoperoxide fragmentation in aqueous solution

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid.

Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers.

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity.

P304

917-923

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1111/J.1471-4159.2005.03586.X

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

96

http://www.w3.org/2001/XMLSchema#string

P577

2006-01-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7360394

http://www.w3.org/2001/XMLSchema#string

P698

16412101

http://www.w3.org/2001/XMLSchema#string

P921

P932

1621054

http://www.w3.org/2001/XMLSchema#string