Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells
about
Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implicationsZinc transporter 8 (ZnT8) and β cell functionThe metal face of protein tyrosine phosphatase 1BZinc transporters and zinc signaling: new insights into their role in type 2 diabetesSelectivity and specificity of small molecule fluorescent dyes/probes used for the detection of Zn2+ and Ca2+ in cellsZinc transporters and their role in the pancreatic β-cell.Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cellsProtective antioxidant and antiapoptotic effects of ZnCl2 in rat pancreatic islets cultured in low and high glucose concentrations.Paradoxical zinc toxicity and oxidative stress in the mammary gland during marginal dietary zinc deficiency.Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells.Insulin production hampered by intermittent hypoxia via impaired zinc homeostasis.Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.Zinc inhibits Hedgehog autoprocessing: linking zinc deficiency with Hedgehog activationCharacterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion.Physiologic implications of metal-ion transport by ZIP14 and ZIP8Zinc transporters, mechanisms of action and therapeutic utility: implications for type 2 diabetes mellitus.Zinc biochemistry: from a single zinc enzyme to a key element of life.Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia.Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.ZnT3: a zinc transporter active in several organs.Zinc, pancreatic islet cell function and diabetes: new insights into an old story.Zinc and insulin in pancreatic beta-cells.Genetically-encoded FRET-based sensors for monitoring Zn(2+) in living cells.Analyzing free zinc(II) ion concentrations in cell biology with fluorescent chelating molecules.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.Induction of endoplasmic reticulum stress and changes in expression levels of Zn(2+)-transporters in hypertrophic rat heart.Exogenous metallothionein potentiates the insulin response at normal glucose concentrations in INS-1E beta-cells without disturbing intracellular ZnT8 expression.Rising intracellular zinc by membrane depolarization and glucose in insulin-secreting clonal HIT-T15 beta cells.Predicting the functions of long noncoding RNAs using RNA-seq based on Bayesian network.Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets.eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn(2+) Imaging.Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project.Dynamic imaging of cytosolic zinc in Arabidopsis roots combining FRET sensors and RootChip technology.Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism.Selenium supplementation modulates zinc levels and antioxidant values in blood and tissues of diabetic rats fed zinc-deficient diet.Understanding the Contribution of Zinc Transporters in the Function of the Early Secretory Pathway.The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
P2860
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P2860
Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@ast
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@en
type
label
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@ast
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@en
prefLabel
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@ast
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@en
P2860
P356
P1476
Glucose regulates free cytosol ...... imary pancreatic islet β-cells
@en
P2093
Gargi Meur
Guy A Rutter
P2860
P304
25778-25789
P356
10.1074/JBC.M111.246082
P407
P577
2011-05-25T00:00:00Z