Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.

Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.

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http://www.wikidata.org/entity/Q35110943

Q35110943

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IGF-IR: a new prognostic biomarker for human glioblastoma miR-219-5p inhibits receptor tyrosine kinase pathway by targeting EGFR in glioblastoma.The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion Expression of IMP3 as a marker for predicting poor outcome in gastroenteropancreatic neuroendocrine neoplasms.Gene expression profile during proliferation and differentiation of rainbow trout adipocyte precursor cells.Role of IGF2BP3 in trophoblast cell invasion and migration IMP3 expression is associated with epithelial-mesenchymal transition in breast cancer.CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity.IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer.Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway Regulation of IMP3 by EGFR signaling and repression by ERβ: implications for triple-negative breast cancer.Unique sex-based approach identifies transcriptomic biomarkers associated with non-syndromic craniosynostosis.Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway.Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) as a Useful Immunohistochemical Marker for the Diagnosis of Adenocarcinoma of Small Intestine.Comprehensive profiling of novel microRNA-9 targets and a tumor suppressor role of microRNA-9 via targeting IGF2BP1 in hepatocellular carcinoma.Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation.Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication.Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?Stimulation of MMP-1 and CCL2 by NAMPT in PDL cells.Posttranscriptional regulation of insulin family ligands and receptors Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance.Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment.IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis.Systematic review of protein biomarkers of invasive behavior in glioblastoma.iTRAQ-Based Quantitative Proteomic Analyses of High Grade Esophageal Squamous Intraepithelial Neoplasia.Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma.IGF2BP1: a novel binding protein of p38 MAPK.MicroRNA-129-1 acts as tumour suppressor and induces cell cycle arrest of GBM cancer cells through targeting IGF2BP3 and MAPK1.IL-18-induced interaction between IMP3 and HuR contributes to COX-2 mRNA stabilization in acute myeloid leukemia.miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma.Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation.The zinc finger transcription factor ZKSCAN3 promotes prostate cancer cell migration.Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation.Genome-wide methylation analysis of retrocopy-associated CpG islands and their genomic environment.IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65.The oncofetal protein IMP3: a novel grading tool and predictor of poor clinical outcome in human gliomas.

P2860

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P2860

Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.

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