Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
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CardioGxE, a catalog of gene-environment interactions for cardiometabolic traitsNeuroendorine and Epigentic Mechanisms Subserving Autonomic Imbalance and HPA Dysfunction in the Metabolic SyndromeRecent progress in genetic and epigenetic research on type 2 diabetesComorbidity between Type 2 Diabetes and Depression in the Adult Population: Directions of the Association and Its Possible Pathophysiological MechanismsDNA modifications: function and applications in normal and disease StatesEpigenetic Regulation of Islet Development and RegenerationDifferential methylation of TCF7L2 promoter in peripheral blood DNA in newly diagnosed, drug-naïve patients with type 2 diabetes2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implicationsDifferential DNA methylation of MSI2 and its correlation with diabetic traits.A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data.Integrating transcriptome and epigenome: putting together the pieces of the type 2 diabetes pathogenesis puzzle.The Pancreatic Islet Regulome Browser.β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner.Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.β cells keep bad epigenetic memories of palmitate.The Missing lnc(RNA) between the pancreatic β-cell and diabetesGene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg DebateAssociations between changes in the maternal gut microbiome and differentially methylated regions of diabetes-associated genes in fetuses: A pilot study from a birth cohort studyGlobal genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolismGenome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.The pancreatic β cell: recent insights from human genetics.A systems view of epigenetic networks regulating pancreas development and β-cell functionGenome-wide DNA methylation profiles indicate CD8+ T cell hypermethylation in multiple sclerosisThe potential use of DNA methylation biomarkers to identify risk and progression of type 2 diabetes.Aging and DNA methylation.Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.Heritable IUGR and adult metabolic syndrome are reversible and associated with alterations in the metabolome following dietary supplementation of 1-carbon intermediates.Insights from GWAS: emerging landscape of mechanisms underlying complex trait diseaseThe BisPCR(2) method for targeted bisulfite sequencing.Network Cluster Analysis of Protein-Protein Interaction Network-Identified Biomarker for Type 2 Diabetes.Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.Rfx6 maintains the functional identity of adult pancreatic β cells.Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.DNA methylation directs functional maturation of pancreatic β cells.A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren.Differential DNA methylation identified in the blood and retina of AMD patients.
P2860
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P2860
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
description
2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Genome-wide DNA methylation an ...... t influence insulin secretion.
@ast
Genome-wide DNA methylation an ...... t influence insulin secretion.
@en
type
label
Genome-wide DNA methylation an ...... t influence insulin secretion.
@ast
Genome-wide DNA methylation an ...... t influence insulin secretion.
@en
prefLabel
Genome-wide DNA methylation an ...... t influence insulin secretion.
@ast
Genome-wide DNA methylation an ...... t influence insulin secretion.
@en
P2093
P2860
P50
P1433
P1476
Genome-wide DNA methylation an ...... t influence insulin secretion.
@en
P2093
Anders H Olsson
Claes B Wollheim
Emma Nilsson
Petr Volkov
Sofia Salö
Tasnim Dayeh
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004160
P577
2014-03-06T00:00:00Z