Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. - Wikidata - awgldk - TriplyDB

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.

http://www.wikidata.org/entity/Q35114942

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Expression of nuclear factor-kappa B in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus Notch1 augments NF-kappaB activity by facilitating its nuclear retention Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis Is there a role for Notch signalling in human breast cancer?Alterations induced by chronic stress in lymphocyte subsets of blood and primary and secondary immune organs of mice Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies The Link between Autoimmunity and Lymphoma: Does NOTCH Signaling Play a Contributing Role?Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord Deciphering the pathway from the TCR to NF-kappaB Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line.Functional diversity of notch family genes in fetal lung development Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine Presenilins regulate alphabeta T cell development by modulating TCR signaling Cardiac-specific genetic inhibition of nuclear factor-κB prevents right ventricular hypertrophy induced by monocrotaline.Deletion of PKBalpha/Akt1 affects thymic development RelB-dependent stromal cells promote T-cell leukemogenesis Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.Presenilin-dependent gamma-secretase activity modulates thymocyte development.Notch1 confers a resistance to glucocorticoid-induced apoptosis on developing thymocytes by down-regulating SRG3 expression Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.Current views on the role of Notch signaling and the pathogenesis of human leukemia.Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice Notch inhibitors for cancer treatment.Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.Lymphostromal interactions in thymic development and function.Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia.Dynamic changes in E-protein activity regulate T reg cell development.Notch signaling and the bone marrow hematopoietic stem cell niche.Notch signaling in hematopoiesis and early lymphocyte development.c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.

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Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.

http://www.wikidata.org/entity/Q35114942

description

2000 nî lūn-bûn

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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հուլիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Constitutive activation of NF- ...... oma in Notch3 transgenic mice.

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Constitutive activation of NF- ...... oma in Notch3 transgenic mice.

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P2860

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells

T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells

Notch signaling: cell fate control and signal integration in development

RORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma / TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter

Aberrant rel/nfkb genes and activity in human cancer

The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition

Notch signalling controls pancreatic cell differentiation

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3337-3348

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13

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