An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease - Wikidata - awgldk - TriplyDB

An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

http://www.wikidata.org/entity/Q35117334

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Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients.TOMM40 rs2075650 may represent a new candidate gene for vulnerability to major depressive disorder.Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease.Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease.Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE Developing novel blood-based biomarkers for Alzheimer's disease Cellular source-specific effects of apolipoprotein (apo) E4 on dendrite arborization and dendritic spine development.TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease.ENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice.Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.Promising Genetic Biomarkers of Preclinical Alzheimer's Disease: The Influence of APOE and TOMM40 on Brain Integrity.Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.Alzheimer's disease: a clinical practice-oriented review.Autosomal recessive causes likely in early-onset Alzheimer disease.Associations Between Genetic Variants in 19p13 and 19q13 Regions and Susceptibility to Alzheimer Disease: A Meta-Analysis The Role of Upregulated APOE in Alzheimer's Disease Etiology.Apolipoprotein e sets the stage: response to injury triggers neuropathology.Imaging the Alzheimer brain.The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.Amyloid precursor protein processing and Alzheimer's disease Modeling the dementia epidemic.Relationship between genetic risk factors and markers for Alzheimer's disease pathology.Biomarker-driven therapeutic management of Alzheimer's disease: establishing the foundations.TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype.The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease.Mitochondria, Cybrids, Aging, and Alzheimer's Disease.Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant.Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers.APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds.Characterization of APOE and TOMM40 allele frequencies in the Japanese population.TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer's Disease Subjects.Mitochondria and Mitochondrial Cascades in Alzheimer's Disease.Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease.Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants.Computer-Aided Multi-Target Management of Emergent Alzheimer's Disease.Commentary on Functional analysis of APOE Locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE

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An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

http://www.wikidata.org/entity/Q35117334

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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type

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An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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prefLabel

An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease

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Allen D Roses

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P2860

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells.

A century of Alzheimer's disease.

Genetics of Alzheimer's disease: recent advances.

Perspective on a pathogenesis and treatment of Alzheimer's disease.

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