Amyloid precursor protein processing and Alzheimer's disease
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A synthetic peptide with the putative iron binding motif of amyloid precursor protein (APP) does not catalytically oxidize ironCanonical and Non-canonical Reelin SignalingMicroRNAs: Key Regulators in the Central Nervous System and Their Implication in Neurological DiseasesAlzheimer's disease: the silver tsunami of the 21(st) centuryA Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsAn overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levelsMouse Genetic Models of Human Brain DisordersRole of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation "in vivo" by P2X7 receptorThe genetics and neuropathology of Alzheimer's diseaseAt the interface of sensory and motor dysfunctions and Alzheimer's disease.Amyloid-β and APP deficiencies cause severe cerebrovascular defects: important work for an old villainHippocampal network oscillations in APP/APLP2-deficient miceThe Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds CholesterolFactors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin MutantsOxidative stress in Alzheimer's and Parkinson's diseases: insights from the yeast Saccharomyces cerevisiaeAbeta, oxidative stress in Alzheimer disease: evidence based on proteomics studiesNeurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?Non-coding RNA in neural function, disease, and agingThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseNMR structure of the water soluble Aβ17-34 peptideALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseAmyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assembliesModulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's diseaseMagnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer's modelAmyloid is linked to cognitive decline in patients with Parkinson disease without dementiaSynthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholTargeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer's disease-related pathogenesisAn improved workflow for quantitative N-terminal charge-based fractional diagonal chromatography (ChaFRADIC) to study proteolytic events in Arabidopsis thaliana.Identification of fibrillogenic regions in human triosephosphate isomerase.Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.Alzheimer's disease: pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents.Convergent genetic and expression data implicate immunity in Alzheimer's diseaseNeurobiology of Alzheimer's Disease: Integrated Molecular, Physiological, Anatomical, Biomarker, and Cognitive Dimensions(-)-Epigallocatechin-3-gallate ameliorates learning and memory deficits by adjusting the balance of TrkA/p75NTR signaling in APP/PS1 transgenic mice.PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and AβBeneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteriesThe Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative DiseasesMultifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative DisordersPolymicrobial Infections In Brain Tissue From Alzheimer's Disease PatientsNon-neuronal cells exacerbate β-amyloid aggregation in the aged brain.
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P2860
Amyloid precursor protein processing and Alzheimer's disease
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Amyloid precursor protein processing and Alzheimer's disease
@en
Amyloid precursor protein processing and Alzheimer's disease.
@nl
type
label
Amyloid precursor protein processing and Alzheimer's disease
@en
Amyloid precursor protein processing and Alzheimer's disease.
@nl
prefLabel
Amyloid precursor protein processing and Alzheimer's disease
@en
Amyloid precursor protein processing and Alzheimer's disease.
@nl
P2860
P1476
Amyloid precursor protein processing and Alzheimer's disease
@en
P2093
Philip C Wong
Richard J O'Brien
P2860
P304
P356
10.1146/ANNUREV-NEURO-061010-113613
P577
2011-01-01T00:00:00Z