Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
about
The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25B-CDK2/Cyclin A interaction using computational approaches.Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategiesInsights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25.Identification of the quinolinedione inhibitor binding site in Cdc25 phosphatase B through docking and molecular dynamics simulations.Role of single disulfide linkages in the folding and activity of scyllatoxin-based BH3 domain mimetics.
P2860
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P2860
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
description
2014 nî lūn-bûn
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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@ast
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@en
type
label
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@ast
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@en
prefLabel
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@ast
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@en
P2093
P2860
P356
P1433
P1476
Inhibition of CDC25B phosphatase through disruption of protein-protein interaction
@en
P2093
Dmitry Borkin
George Lund
Jolanta Grembecka
Sergii Dudkin
Tomasz Cierpicki
P2860
P304
P356
10.1021/CB500883H
P577
2014-12-01T00:00:00Z