Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family. - Wikidata - awgldk - TriplyDB

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family.

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family.

http://www.wikidata.org/entity/Q35123262

about

The molecular pharmacology of volatile anesthetics The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily Chimeragenesis of distantly-related proteins by noncontiguous recombination Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel A locally closed conformation of a bacterial pentameric proton-gated ion channel Open-channel structures of the human glycine receptor α1 full-length transmembrane domain.Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses Glycine receptor mouse mutants: model systems for human hyperekplexia Identification of a pre-active conformation of a pentameric channel receptor ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation.An internally modulated, thermostable, pH-sensitive Cys loop receptor from the hydrothermal vent worm Alvinella pompejana Computational design of membrane proteins.Atomistic insights into human Cys-loop receptors by solution NMR.Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors.Structural basis for alcohol modulation of a pentameric ligand-gated ion channel Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure Engineering a prokaryotic Cys-loop receptor with a third functional domain.Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors.Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation.Role of the Fourth Transmembrane α Helix in the Allosteric Modulation of Pentameric Ligand-Gated Ion Channels.Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel.Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites Intermediate closed state for glycine receptor function revealed by cysteine cross-linking.Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics.Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics The energy and work of a ligand-gated ion channel.Pentameric Ligand-gated Ion Channels : Insights from Computation.A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Genuine open form of the pentameric ligand-gated ion channel GLIC.The M4 Transmembrane α-Helix Contributes Differently to Both the Maturation and Function of Two Prokaryotic Pentameric Ligand-gated Ion Channels.Probing residues in the pore-forming (M2) domain of the Cys-loop receptor homologue GLIC reveals some unusual features.The importance of TM3-4 loop subdomains for functional reconstitution of glycine receptors by independent domains.Structural requirements in the transmembrane domain of GLIC revealed by incorporation of noncanonical histidine analogs.Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).Potentiators exert distinct effects on human, murine, and Xenopus CFTR.Binding site and affinity prediction of general anesthetics to protein targets using docking.

P2860

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P2860

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family.

http://www.wikidata.org/entity/Q35123262

description

2011 nî lūn-bûn

@nan

2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@ast

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@en

type

label

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@ast

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@en

prefLabel

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@ast

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@en

P1433

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P2860

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P356

PNAS.1104494108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Functional prokaryotic-eukaryo ...... gand-gated ion channel family.

@en

P2093

Catherine Van Renterghem

http://www.w3.org/2001/XMLSchema#string

Christèle Huon

http://www.w3.org/2001/XMLSchema#string

Guillaume Duret

http://www.w3.org/2001/XMLSchema#string

Gustavo Moraga-Cid

http://www.w3.org/2001/XMLSchema#string

James M Sonner

http://www.w3.org/2001/XMLSchema#string

Marie Prevost

http://www.w3.org/2001/XMLSchema#string

Pierre-Jean Corringer

http://www.w3.org/2001/XMLSchema#string

Yun Weng

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

Principles of activation and permeation in an anion-selective Cys-loop receptor

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers

P304

12143-12148

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P31

scholarly article

P356

10.1073/PNAS.1104494108

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P407

P433

29

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P478

108

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2011-07-05T00:00:00Z

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P5875

51468210

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P698

21730130

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P932

3141993

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