Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias.
about
PTH receptor-1 signalling-mechanistic insights and therapeutic prospectsLessons learned from the clinical development of oral peptides.The role of kinetic context in apparent biased agonism at GPCRs.Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics.Bone-seeking agents for the treatment of bone disorders.Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25.Biased signalling: from simple switches to allosteric microprocessors.KBP-088, a novel DACRA with prolonged receptor activation, is superior to davalintide in terms of efficacy on body weight.A kinetic view of GPCR allostery and biased agonism.Optimization of tolerability and efficacy of the novel dual amylin and calcitonin receptor agonist KBP-089 through dose escalation and combination with a GLP-1 analog.Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy.
P2860
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P2860
Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias.
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@ast
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@en
type
label
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@ast
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@en
prefLabel
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@ast
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@en
P2093
P2860
P50
P1433
P1476
Prolonged calcitonin receptor ...... lcitonin, reveals ligand bias.
@en
P2093
Kim Henriksen
Kim Vietz Andreassen
Morten Asser Karsdal
Olivier Nosjean
Sara Toftegaard Hjuler
P2860
P304
P356
10.1371/JOURNAL.PONE.0092042
P407
P577
2014-03-18T00:00:00Z