Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
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Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug DesignSchistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitorExpression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasiteBlocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine.Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.Antimalarial activity of azadipeptide nitrilesAntimalarial synergy of cysteine and aspartic protease inhibitors.Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparumAntimalarial activities of novel synthetic cysteine protease inhibitors.Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites.Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones.Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies.The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica.Compounds from Sorindeia juglandifolia (Anacardiaceae) exhibit potent anti-plasmodial activities in vitro and in vivo.Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies.Non-canonical maturation of two papain-family proteases in Toxoplasma gondii.Proteases of malaria parasites: new targets for chemotherapy.Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition.Imidazoquines as antimalarial and antipneumocystis agents.Cathepsin proteases in Toxoplasma gondii.Proteases as regulators of pathogenesis: examples from the Apicomplexa.BDA-410: a novel synthetic calpain inhibitor active against blood stage malaria.Expression and alteration of the S2 subsite of the Leishmania major cathepsin B-like cysteine protease.Antimalarial activity of thiosemicarbazones and purine derived nitriles.Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery.Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents.Allosteric Site Inhibitor Disrupting Auto-Processing of Malarial Cysteine Proteases
P2860
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P2860
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@ast
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@en
type
label
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@ast
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@en
prefLabel
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@ast
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@en
P2093
P2860
P1476
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
@en
P2093
P2860
P304
P407
P577
1996-07-01T00:00:00Z