Rapid evolutionary rewiring of a structurally constrained eye enhancer.
about
Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expressionRegulatory Principles Governing Tissue Specificity of Developmental EnhancersEvolution of New cis-Regulatory Motifs Required for Cell-Specific Gene Expression in CaenorhabditisPhylum-Level Conservation of Regulatory Information in Nematodes despite Extensive Non-coding Sequence DivergenceMechanisms of mutational robustness in transcriptional regulationPervasive divergence of transcriptional gene regulation in Caenorhabditis nematodesWhat does it take to evolve an enhancer? A simulation-based study of factors influencing the emergence of combinatorial regulationCis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergenceGene regulatory network plasticity predates a switch in function of a conserved transcription regulatorAbsence of a simple code: how transcription factors read the genomeTempo and mode in evolution of transcriptional regulation.Role of architecture in the function and specificity of two Notch-regulated transcriptional enhancer modules.Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution.Coevolution within and between regulatory loci can preserve promoter function despite evolutionary rate acceleration.Recurrent modification of a conserved cis-regulatory element underlies fruit fly pigmentation diversitySubtle changes in motif positioning cause tissue-specific effects on robustness of an enhancer's activity.Identifying transcriptional cis-regulatory modules in animal genomes.Handling Permutation in Sequence Comparison: Genome-Wide Enhancer Prediction in Vertebrates by a Novel Non-Linear Alignment Scoring Principle.Genome-wide identification of hypoxia-induced enhancer regionsIntersecting transcription networks constrain gene regulatory evolutionFunction does not follow form in gene regulatory circuitsDivergent MLS1 Promoters Lie on a Fitness Plateau for Gene Expression.An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1.Pax7 is regulated by cMyb during early neural crest development through a novel enhancerSuboptimization of developmental enhancersSyntax compensates for poor binding sites to encode tissue specificity of developmental enhancersSimulations of enhancer evolution provide mechanistic insights into gene regulation.Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex.Impacts of the ubiquitous factor Zelda on Bicoid-dependent DNA binding and transcription in Drosophila.Ancestral resurrection of the Drosophila S2E enhancer reveals accessible evolutionary paths through compensatory change.Chromatin and epigenetic features of long-range gene regulation.Ancestral and conserved cis-regulatory architectures in developmental control genesThe Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Rainbow Enhancers Regulate Restrictive Transcription in Teleost Green, Red, and Blue Cones.Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution.Dissecting sources of quantitative gene expression pattern divergence between Drosophila species.How to tune an enhancer.How transcription circuits explore alternative architectures while maintaining overall circuit output.The evolutionary origination of a novel expression pattern through an extreme heterochronic shift.Automated tools for comparative sequence analysis of genic regions using the GenePalette application.
P2860
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P2860
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@ast
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@en
type
label
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@ast
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@en
prefLabel
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@ast
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@en
P2093
P2860
P1433
P1476
Rapid evolutionary rewiring of a structurally constrained eye enhancer.
@en
P2093
Christina I Swanson
David B Schwimmer
Scott Barolo
P2860
P304
P356
10.1016/J.CUB.2011.05.056
P407
P577
2011-07-07T00:00:00Z