Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. - Wikidata - awgldk - TriplyDB

Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1.

Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1.

http://www.wikidata.org/entity/Q35127580

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CDK1 promotes cell proliferation and survival via phosphorylation and inhibition of FOXO1 transcription factor Regulation of steroid hormone receptors and coregulators during the cell cycle highlights potential novel function in addition to roles as transcription factors Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.Androgen Receptor Exon 1 Mutation Causes Androgen Insensitivity by Creating Phosphorylation Site and Inhibiting Melanoma Antigen-A11 Activation of NH2- and Carboxyl-terminal Interaction-dependent Transactivation αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor.Cell-cycle-dependent regulation of androgen receptor function Androgen receptor phosphorylation: biological context and functional consequences.Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5 CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1 Cyclin-dependent kinase 5 acts as a critical determinant of AKT-dependent proliferation and regulates differential gene expression by the androgen receptor in prostate cancer cells Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells CR6-interacting factor 1 represses the transactivation of androgen receptor by direct interaction.Kinase modulation of androgen receptor signaling: implications for prostate cancer TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.Identification of androgen receptor phosphorylation in the primate ovary in vivo.The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer.Phosphorylation and activation of androgen receptor by Aurora-A An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cells Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer.Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding Mechanisms mediating androgen receptor reactivation after castration.Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement Kinases and protein phosphorylation as regulators of steroid hormone action Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation.Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.Stable Isotope Labeling with Amino Acids (SILAC)-Based Proteomics of Primary Human Kidney Cells Reveals a Novel Link between Male Sex Hormones and Impaired Energy Metabolism in Diabetic Kidney Disease.Inhibitor of p52 NF-κB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated AR(ser81).Androgen receptor serine 81 mediates Pin1 interaction and activity.Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor.Inhibition of glycogen synthase kinase-3 in androgen-responsive prostate cancer cell lines: are GSK inhibitors therapeutically useful?The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells Prediction of functional phosphorylation sites by incorporating evolutionary information Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis

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P2860

Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1.

http://www.wikidata.org/entity/Q35127580

description

2006 nî lūn-bûn

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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

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Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

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type

label

Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

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Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

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prefLabel

Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

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Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

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PNAS.0604193103

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Proceedings of the National Academy of Sciences of the United States of America

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Androgen receptor phosphorylat ...... by cyclin-dependent kinase 1.

@en

P2093

Glenn J Bubley

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Shaoyong Chen

http://www.w3.org/2001/XMLSchema#string

Steven P Balk

http://www.w3.org/2001/XMLSchema#string

Xin Yuan

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Youyuan Xu

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P2860

Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF

From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator

Molecular determinants of resistance to antiandrogen therapy

Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation

Cyclin-dependent kinase pathways as targets for cancer treatment

Roscovitine targets, protein kinases and pyridoxal kinase

Cyclin B1 and CDK1: nuclear localization and upstream regulators

Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites.

Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells.

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103

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phosphorylation

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