Mismatch repair proficiency and in vitro response to 5-fluorouracil. - Wikidata - awgldk - TriplyDB

Mismatch repair proficiency and in vitro response to 5-fluorouracil.

Mismatch repair proficiency and in vitro response to 5-fluorouracil.

http://www.wikidata.org/entity/Q35129256

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MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications Microsatellite instability in colorectal cancer DNA mismatch repair: molecular mechanism, cancer, and ageing Increased sensitivity of p53-deficient cells to anticancer agents due to loss of Pms2 Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines.Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil Role of Deficient Mismatch Repair in the Personalized Management of Colorectal Cancer Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells 8-Cl-adenosine-induced inhibition of colorectal cancer growth in vitro and in vivo Molecular predictors of survival after adjuvant chemotherapy for colon cancer Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma Genomic Profiling in Gastrointestinal Cancer: Are We Ready To Use These Data to Make Treatment Decisions?Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer.Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H).An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents Allelic imbalance at p53 and microsatellite instability are predictive markers for resistance to chemotherapy in gastric carcinoma Genomic and epigenetic instability in colorectal cancer pathogenesis.Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters Differential expression of miRNAs in colon cancer between African and Caucasian Americans: implications for cancer racial health disparities.Clement Richard Boland, Jr., MD: a conversation with the editor. Interview by William Clifford Roberts Clinical relevance of microsatellite instability in colorectal cancer.Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 years 5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.Both hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.Clinicopathological features and microsatellite instability (MSI) in colorectal cancers from African Americans.Making sense of missense in Lynch syndrome: the clinical perspective Methylation and colorectal cancer.Systemic treatment of advanced colorectal cancer: tailoring therapy to the tumor.Prognostic Impact of Deficient DNA Mismatch Repair and Mutations in KRAS, and BRAF(V600E) in Patients with Lymph Node-Positive Colon Cancer How Can Next-Generation Sequencing (Genomics) Help Us in Treating Colorectal Cancer?DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

http://www.wikidata.org/entity/Q35129256

description

1999 nî lūn-bûn

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1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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Gastroenterology

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Mismatch repair proficiency and in vitro response to 5-fluorouracil.

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C R Boland

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D Fink

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D P Chauhan

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Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

Mutation of a mutL homolog in hereditary colon cancer

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Transcription-coupled repair deficiency and mutations in human mismatch repair genes

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

Mutations of GTBP in genetically unstable cells

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

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10381918

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4343206

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