Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand.
about
Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cellsPrimPol, an archaic primase/polymerase operating in human cellsMitochondrial DNA replication and disease: insights from DNA polymerase γ mutationsOxidative stress, mitochondrial dysfunction, and agingThe mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNAHuman mitochondrial DNA replicationMitochondrial DNA: A disposable genome?A rolling circle replication mechanism produces multimeric lariats of mitochondrial DNA in Caenorhabditis elegansSequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromesEnzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replicationAnalysis of enzyme kinetic data for mtDNA replication.Mitochondrial DNA replication: a PrimPol perspective.Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy numberEffects on mitochondrial transcription of manipulating mTERF protein levels in cultured human HEK293 cells.A mechanistic view of human mitochondrial DNA polymerase gamma: providing insight into drug toxicity and mitochondrial diseaseMammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid.Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern ChinaAn upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels.Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease.RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial EncephalomyopathyAnalysis of replication intermediates indicates that Drosophila melanogaster mitochondrial DNA replicates by a strand-coupled theta mechanism.A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties.Mitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis.Mitochondrial DNA mutations in disease and agingOrigins and functional consequences of somatic mitochondrial DNA mutations in human cancerThe mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimersTransfection of plant mitochondria and in organello gene integration.The inversion of the Control Region in three mitogenomes provides further evidence for an asymmetric model of vertebrate mtDNA replication.Evolution of the metazoan mitochondrial replicase.Tandem Duplication and Random Loss for mitogenome rearrangement in Symphurus (Teleost: Pleuronectiformes).Maintaining ancient organelles: mitochondrial biogenesis and maturation.Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.Animal models of mitochondrial DNA transactions in disease and ageingMPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in MitochondriaThe interface of transcription and DNA replication in the mitochondriaPrimer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication.Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.Low doses of ultraviolet radiation and oxidative damage induce dramatic accumulation of mitochondrial DNA replication intermediates, fork regression, and replication initiation shiftNucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA.
P2860
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P2860
Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年学术文章
@wuu
2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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name
Replication of vertebrate mito ...... throughout the lagging strand.
@ast
Replication of vertebrate mito ...... throughout the lagging strand.
@en
type
label
Replication of vertebrate mito ...... throughout the lagging strand.
@ast
Replication of vertebrate mito ...... throughout the lagging strand.
@en
prefLabel
Replication of vertebrate mito ...... throughout the lagging strand.
@ast
Replication of vertebrate mito ...... throughout the lagging strand.
@en
P2093
P2860
P50
P356
P1433
P1476
Replication of vertebrate mito ...... throughout the lagging strand
@en
P2093
Aurelio Reyes
Mark Bowmaker
Takehiro Yasukawa
Tricia J Cluett
P2860
P304
P356
10.1038/SJ.EMBOJ.7601392
P407
P577
2006-10-26T00:00:00Z