Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression. - Wikidata - awgldk - TriplyDB

Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression.

Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression.

http://www.wikidata.org/entity/Q35131575

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Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis Cardiovascular actions of neurotrophins Nerve growth factor promotes breast cancer angiogenesis by activating multiple pathways.Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells.Trk receptor expression and inhibition in neuroblastomas Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis.C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B TrkC expression predicts favorable clinical outcome in invasive ductal carcinoma of breast independent of NT-3 expression.The interaction between epigenetics, nutrition and the development of cancer Nerve growth factor involvement in liver cirrhosis and hepatocellular carcinoma.A novel analysis strategy for integrating methylation and expression data reveals core pathways for thyroid cancer aetiology.Identification of pyrazine-based TrkA inhibitors: design, synthesis, evaluation, and computational modeling studies.The dark side of the NGF family: neurotrophins in neoplasias.Genetic alterations in thyroid cancer: the role of mouse models.High-affinity neurotrophin receptors and ligands promote leukemogenesis.ProNGF is a potential diagnostic biomarker for thyroid cancer Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma.Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy TrkC promotes survival and growth of leukemia cells through Akt-mTOR-dependent up-regulation of PLK-1 and Twist-1.On Trk--the TrkB signal transduction pathway is an increasingly important target in cancer biology.Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations.Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer.RET TKI: potential role in thyroid cancers.A novel microRNA located in the TrkC gene regulates the Wnt signaling pathway and is differentially expressed in colorectal cancer specimens.Small Molecules for Active Targeting in Cancer.Role of the autonomic nervous system in tumorigenesis and metastasis Experimental verification of a conserved intronic microRNA located in the human TrkC gene with a cell type-dependent apoptotic function.TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts.Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy.Analysis of the interplay between methylation and expression reveals its potential role in cancer aetiology.AZ64 inhibits TrkB and enhances the efficacy of chemotherapy and local radiation in neuroblastoma xenografts.Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models.c-Src is required for tropomyosin receptor kinase C (TrkC)-induced activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway.Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas.Activation of trkA induces differentiation and inhibits the growth of JK-GMS Askin tumor cells.Expression of neurotrophin receptor TrkA inhibits angiogenesis in neuroblastoma.Synergistic activity of everolimus and 5-aza-2'-deoxycytidine in medullary thyroid carcinoma cell lines.Trks are novel oncogenes involved in the induction of neovascularization, tumor progression, and nodal metastasis in oral squamous cell carcinoma.Brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma.

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Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression.

http://www.wikidata.org/entity/Q35131575

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1999 nî lūn-bûn

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1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1999 թվականի ապրիլին հրատարակված գիտական հոդված

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1999年の論文

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Roles of trk family neurotroph ...... a development and progression.

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Roles of trk family neurotroph ...... a development and progression.

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Roles of trk family neurotroph ...... a development and progression.

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Roles of trk family neurotroph ...... a development and progression.

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Proceedings of the National Academy of Sciences of the United States of America

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Roles of trk family neurotroph ...... a development and progression.

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P2093

B D Nelkin

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P2860

Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant

Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B

Molecular and biochemical characterization of the human trk proto-oncogene

Improved retroviral vectors for gene transfer and expression.

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells

Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma.

Expression and function of TRK-B and BDNF in human neuroblastomas

Expression of trkA cDNA in neuroblastomas mediates differentiation in vitro and in vivo.

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