Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer
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Signaling cross-talk in the resistance to HER family receptor targeted therapyRegulators associated with clinical outcomes revealed by DNA methylation data in breast cancer.mRNA expression of DOK1-6 in human breast cancerActivity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypesAssessing the Racial and Ethnic Disparities in Breast Cancer Mortality in the United StatesEstrogen regulation of anti-apoptotic Bcl-2 family member Mcl-1 expression in breast cancer cellsEvaluation of apoptosis induction by concomitant inhibition of MEK, mTOR, and Bcl-2 in human acute myelogenous leukemia cells.LIN-3/EGF promotes the programmed cell death of specific cells in Caenorhabditis elegans by transcriptional activation of the pro-apoptotic gene egl-1.Histone deacetylase inhibitors facilitate dihydroartemisinin-induced apoptosis in liver cancer in vitro and in vivo.Cyr61 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway.Learning contextual gene set interaction networks of cancer with condition specificityPaclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.Myeloid cell leukemia 1 (Mcl(-1)) protects against 1-methyl-4-phenylpyridinium ion (MPP+) induced apoptosis in Parkinson's disease.Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications.Regulation of ubiquitination-mediated protein degradation by survival kinases in cancer.Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosisBroad targeting of resistance to apoptosis in cancer.Epigenetic silencing of tumor suppressor miR-3151 contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways.BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomasLapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells.Automated Quantitative Analysis of p53, Cyclin D1, Ki67 and pERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics.Flavopiridol synergizes with sorafenib to induce cytotoxicity and potentiate antitumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems.RNA-dependent dynamic histone acetylation regulates MCL1 alternative splicing.Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs.RegPhos 2.0: an updated resource to explore protein kinase-substrate phosphorylation networks in mammals.That which does not kill me makes me stronger; combining ERK1/2 pathway inhibitors and BH3 mimetics to kill tumour cells and prevent acquired resistance.MicroRNA-451 sensitizes lung cancer cells to cisplatin through regulation of Mcl-1.HCMV activation of ERK-MAPK drives a multi-factorial response promoting the survival of infected myeloid progenitors.Effect of siRNA pre-Exposure on Subsequent Response to siRNA Therapy.Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability.EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells.Proteinase-activated receptor 2 (PAR2) decreases apoptosis in colonic epithelial cells.p53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cells.Polymeric delivery of siRNA for dual silencing of Mcl-1 and P-glycoprotein and apoptosis induction in drug-resistant breast cancer cells.EGFR Family Members' Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer.The miR-30 family: Versatile players in breast cancer.Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling.Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1.Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma.
P2860
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P2860
Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Epidermal growth factor regula ...... cell survival in breast cancer
@ast
Epidermal growth factor regula ...... cell survival in breast cancer
@en
type
label
Epidermal growth factor regula ...... cell survival in breast cancer
@ast
Epidermal growth factor regula ...... cell survival in breast cancer
@en
prefLabel
Epidermal growth factor regula ...... cell survival in breast cancer
@ast
Epidermal growth factor regula ...... cell survival in breast cancer
@en
P2860
P356
P1433
P1476
Epidermal growth factor regula ...... cell survival in breast cancer
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2010.616
P407
P577
2011-01-24T00:00:00Z