p53 downregulates Down syndrome-associated DYRK1A through miR-1246. - Wikidata - awgldk - TriplyDB

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

http://www.wikidata.org/entity/Q35138481

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Exosome platform for diagnosis and monitoring of traumatic brain injury Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein Kinase Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor The evolutionary young miR-1290 favors mitotic exit and differentiation of human neural progenitors through altering the cell cycle proteins.Analysis of differential miRNA expression in primary tumor and stroma of colorectal cancer patients.Mirna expression profiles identify drivers in colorectal and pancreatic cancers.Treatment-independent miRNA signature in blood of Wilms tumor patients.Global effect of inauhzin on human p53-responsive transcriptome Alternative processing of the U2 small nuclear RNA produces a 19-22nt fragment with relevance for the detection of non-small cell lung cancer in human serum.Characterization of microRNA expression profiles and the discovery of novel microRNAs involved in cancer during human embryonic development.Parallel mRNA and microRNA profiling of HEV71-infected human neuroblastoma cells reveal the up-regulation of miR-1246 in association with DLG3 repression The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus.Identification of ncRNAs as potential therapeutic targets in multiple sclerosis through differential ncRNA - mRNA network analysis.Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.The small RNA content of human sperm reveals pseudogene-derived piRNAs complementary to protein-coding genes The microRNA-1246 promotes metastasis in non-small cell lung cancer by targeting cytoplasmic polyadenylation element-binding protein 4 Investigation of Content, Stoichiometry and Transfer of miRNA from Human Neural Stem Cell Line Derived Exosomes.MiR-1246: a new link of the p53 family with cancer and Down syndrome.Transcriptional regulation of microRNA-100, -146a, and -150 genes by p53 and NFκB p65/RelA in mouse striatal STHdh(Q7)/ Hdh(Q7) cells and human cervical carcinoma HeLa cells.MicroRNAs are exported from malignant cells in customized particles.Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function.IκB kinase β (IKKβ) inhibits p63 isoform γ (TAp63γ) transcriptional activity.The origin, function, and diagnostic potential of RNA within extracellular vesicles present in human biological fluids.Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma A set of microRNAs mediate direct conversion of human umbilical cord lining-derived mesenchymal stem cells into hepatocytes.MicroRNA profiling of low-grade glial and glioneuronal tumors shows an independent role for cluster 14q32.31 member miR-487b New insights into p53 functions through its target microRNAs.The p53/microRNA connection in gastrointestinal cancer.Why increased nuchal translucency is associated with congenital heart disease: a systematic review on genetic mechanisms.Identification of circulating microRNAs as potential biomarkers for detecting acute ischemic stroke.DYRK1A inhibition as potential treatment for Alzheimer's disease.Synthetic combinations of missense polymorphic genetic changes underlying Down syndrome susceptibility.miR-1246 releases RTKN2-dependent resistance to UVB-induced apoptosis in HaCaT cells.MiR-1246 promotes SiHa cervical cancer cell proliferation, invasion, and migration through suppression of its target gene thrombospondin 2.Fetal Bovine Serum RNA Interferes with the Cell Culture derived Extracellular RNA Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma.Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells.Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer's disease.

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P2860

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

http://www.wikidata.org/entity/Q35138481

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@ast

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@en

type

label

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@ast

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@en

prefLabel

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@ast

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@en

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p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

@en

P2093

Hua Lu

http://www.w3.org/2001/XMLSchema#string

Jun-Ming Liao

http://www.w3.org/2001/XMLSchema#string

Shelya X Zeng

http://www.w3.org/2001/XMLSchema#string

Yu Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

SSRP1 functions as a co-activator of the transcriptional activator p63

MicroRNAs: target recognition and regulatory functions

p53 represses c-Myc through induction of the tumor suppressor miR-145

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

WAF1, a potential mediator of p53 tumor suppression

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

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811-817

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scholarly article

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10.1038/EMBOR.2011.98

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8

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12

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2011-06-03T00:00:00Z

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51187687

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21637297

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3147276

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