The role of antibodies and B cells in the pathogenesis of lupus nephritis.
about
Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunityBreaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis.Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.SLE: translating lessons from model systems to human diseasePauci-immune and immune glomerular lesions in kidney transplants for systemic lupus erythematosus.Glomerular targets for autoantibodies in lupus nephritis--an apoptotic origin.A central role of nucleosomes in lupus nephritis.Translational Mini-Review Series on B Cell-Directed Therapies: The pathogenic role of B cells in autoantibody-associated autoimmune diseases--lessons from B cell-depletion therapy.Chromatin as a target antigen in human and murine lupus nephritisComplement in the immunopathogenesis of rheumatic disease.Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells.Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation.
P2860
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P2860
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@ast
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@en
type
label
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@ast
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@en
prefLabel
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@ast
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@en
P1476
The role of antibodies and B cells in the pathogenesis of lupus nephritis.
@en
P2093
Mark J Shlomchik
Michael P Madaio
P2888
P304
P356
10.1007/S00281-003-0119-1
P577
2003-05-01T00:00:00Z