Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration. - Wikidata - awgldk - TriplyDB

Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.

Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.

http://www.wikidata.org/entity/Q35143491

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NIH workshop report on the trans-agency blood-brain interface workshop 2016: exploring key challenges and opportunities associated with the blood, brain and their interface.Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer's Disease Biomarkers: A Pilot Clinical Trial.Intranasal insulin treatment of an experimental model of moderate traumatic brain injury.IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury Hello from the Other Side: How Autoantibodies Circumvent the Blood-Brain Barrier in Autoimmune Encephalitis.Nasal administration of the neuroprotective candidate NeuroEPO to healthy volunteers: a randomized, parallel, open-label safety study Small endogenous molecules as moiety to improve targeting of CNS drugs.Rapid intranasal delivery of chloramphenicol acetyltransferase in the active form to different brain regions as a model for enzyme therapy in the CNS.Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery.Intranasal delivery: circumventing the iron curtain to treat neurological disorders.Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET.Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice.Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning.Delivering therapy to target: improving the odds for successful drug development.Impact of Single or Repeated Dose Intranasal Zinc-free Insulin in Young and Aged F344 Rats on Cognition, Signaling, and Brain Metabolism.Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection.Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I.Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats.Advances in brain barriers and brain fluid research and news from Fluids and Barriers of the CNS.Reduced brain insulin signaling: A seminal process in Alzheimer's disease pathogenesis.Effect of administration method, animal weight and age on the intranasal delivery of drugs to the brain.Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.Intranasally administered IGF-1 inhibits spreading depression in vivo.Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse.Demonstration of Nucleoside Transporter Activity in the Nose-to-Brain Distribution of [18F]Fluorothymidine Using PET Imaging.Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on Cognition.Novel calcium-related targets of insulin in hippocampal neurons.Intranasal delivery of stem cell-based therapies for the treatment of brain malignancies.Intranasal Insulin Transport is Preserved in Aged SAMP8 Mice and is Altered by Albumin and Insulin Receptor Inhibition.LC-MS/MS assay of ropinirole in rat biological matrices: elimination of lysoglycerophosphocholines-based matrix effect.Methodology and effects of repeated intranasal delivery of DNSP-11 in awake Rhesus macaques.Insulin Resistance as a Therapeutic Target in the Treatment of Alzheimer's Disease: A State-of-the-Art Review.Subacute intranasal administration of tissue plasminogen activator improves stroke recovery by inducing axonal remodeling in mice.Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood-brain barrier Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

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Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.

http://www.wikidata.org/entity/Q35143491

description

2014 nî lūn-bûn

@nan

2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Rapid transport within cerebra ...... ter intranasal administration.

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Rapid transport within cerebra ...... ter intranasal administration.

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Rapid transport within cerebra ...... ter intranasal administration.

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Rapid transport within cerebra ...... ter intranasal administration.

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Journal of Cerebral Blood Flow & Metabolism

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Rapid transport within cerebra ...... fter intranasal administration

@en

P2093

Daniel J Wolak

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Robert G Thorne

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P2860

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

Transient opening of the perineurial barrier for analgesic drug delivery

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

The olfactory route for cerebrospinal fluid drainage into the peripheral lymphatic system.

Intranasal epidermal growth factor treatment rescues neonatal brain injury.

Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging

Sniffing neuropeptides: a transnasal approach to the human brain.

Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space.

Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit.

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology.

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371-381

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scholarly article

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10.1038/JCBFM.2014.215

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3

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35

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Michelle E Pizzo

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2014-12-10T00:00:00Z

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25492117

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4348383

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