A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice. - Wikidata - awgldk - TriplyDB

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

http://www.wikidata.org/entity/Q35144532

about

Lung carcinogenesis by tobacco smoke Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Combining AKT inhibition with chloroquine and gefitinib prevents compensatory autophagy and induces cell death in EGFR mutated NSCLC cells.Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.miR-124 Inhibits Lung Tumorigenesis Induced by K-ras Mutation and NNK.

P2860

Q24625044-FFB929D2-0E57-4050-887C-85330185785F Q33596274-60BF03B5-92EF-4F63-9576-39F206F6E8CF Q34104025-EA9B3885-0252-472C-8419-E7C6A7FBC53F Q35847688-E51F76E6-B393-4226-B623-6FBE638B25F1 Q36618677-52C71A2D-1ABB-4EF4-89CD-677E63D56B45 Q37412014-998068C9-15CD-48DD-8C7C-129AAE9F4DEF Q39004659-0D3FC9F3-CB9C-42C8-9EF8-05DE2754DFC2 Q47103533-25A46F5B-8CA7-44F9-A0A6-691B9E338CC1

P2860

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

http://www.wikidata.org/entity/Q35144532

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

@ast

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

@en

type

label

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

@ast

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

@en

prefLabel

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

@ast

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

@en

P1433

Q35144532-471C8FEA-5910-4207-AD4E-B2BB563B997B

P1476

Q35144532-7330F816-0242-449D-9C89-3D0A3D82F13E

P2093

Q35144532-75B67502-AD01-4E0B-9F3F-8F5FAF0C3FF4

Q35144532-AE92D700-C430-4D66-B378-15D6E7360633

Q35144532-D8EE403A-11C4-4B20-83FB-28FF7E902E2D

Q35144532-EA96A924-654C-43D0-BAD6-62AFD06802AB

Q35144532-FCD68BA6-9159-4F8A-9829-61AD7C025562

P2860

Q35144532-15D82410-8DB0-4C2D-980B-CC2CC078AA0E

Q35144532-1748C51F-5B01-40FA-A925-7041F4F0C5F8

Q35144532-26E5C4A4-3102-4AE6-BCE9-5348295DA469

Q35144532-274AB7FD-F582-4108-9DB6-084B641FE0CC

Q35144532-30F20DBB-3E53-4230-93AE-1F7C23D52064

Q35144532-40ADD40D-0A1F-4C35-A638-91C6E67212EA

Q35144532-441083BD-E430-40E7-AAE3-774CA0C75424

Q35144532-4A06997C-B46C-4146-9096-5612FAA91D6E

Q35144532-4BE47964-2FEF-4053-9D24-56A0E162985F

Q35144532-4C0EFCDA-3200-4648-8B1A-4992F05FEA38

P304

Q35144532-3A9138FB-4B2F-4FA2-A4D9-75B67FFA9D23

P31

Q35144532-2D7F80C2-935B-4350-9450-720A2E240B5C

P356

Q35144532-6415E7F7-8C7D-4CB6-A278-D5B2322B564F

P407

Q35144532-1C7959F9-069F-4841-B29D-7BBB1724BEE4

P433

Q35144532-4E378F5C-C0D1-41B4-B25C-01BB80A74A41

P478

Q35144532-02BC51B6-E232-45B9-86D4-5D7668C01508

P50

Q35144532-E6E66D6F-05DF-4A65-BD90-A86489C2D5E8

P577

Q35144532-48FD34C6-6D7B-4C6E-9CAE-96160B4E3B2B

P5875

Q35144532-ECBA6802-96B6-49EF-8E1D-5A1651D98566

P698

Q35144532-27A96606-874A-4676-B4F2-5A933B832639

P932

Q35144532-B21879E8-EDFE-4626-82E1-9F3FD49B01AB

P356

P1433

P1476

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice

@en

P2093

Colleen R Maier

http://www.w3.org/2001/XMLSchema#string

M Christine Hollander

http://www.w3.org/2001/XMLSchema#string

Phillip A Dennis

http://www.w3.org/2001/XMLSchema#string

Xin Zhou

http://www.w3.org/2001/XMLSchema#string

Xinxin Ding

http://www.w3.org/2001/XMLSchema#string

P2860

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci.

DNA adduct formation from tobacco-specific N-nitrosamines.

Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Akt1 deletion prevents lung tumorigenesis by mutant K-ras.

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant.

Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK.

P304

1279-1284

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/CARCIN/BGR097

http://www.w3.org/2001/XMLSchema#string

P407

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

32

http://www.w3.org/2001/XMLSchema#string

P50

Andrew Patterson

P577

2011-05-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51177089

http://www.w3.org/2001/XMLSchema#string

P698

21625009

http://www.w3.org/2001/XMLSchema#string

P932

3149208

http://www.w3.org/2001/XMLSchema#string