Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.
about
The hitchhiker's guide to the voltage-gated sodium channel galaxyThe voltage-dependent gate in MthK potassium channels is located at the selectivity filterPaxilline inhibits BK channels by an almost exclusively closed-channel block mechanism.Positions of the cytoplasmic end of BK α S0 helix relative to S1-S6 and of β1 TM1 and TM2 relative to S0-S6.Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91.Cadmium-cysteine coordination in the BK inner pore region and its structural and functional implicationsTungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels.Calcium ions open a selectivity filter gate during activation of the MthK potassium channelSingle Channel Recordings Reveal Differential β2 Subunit Modulations Between Mammalian and Drosophila BKCa(β2) Channels.Perspectives on: conformational coupling in ion channels: conformational coupling in BK potassium channels.Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA.DiBAC₄(3) hits a "sweet spot" for the activation of arterial large-conductance Ca²⁺-activated potassium channels independently of the β₁-subunit.Transduction of voltage and Ca2+ signals by Slo1 BK channels.Structural basis of ion permeation gating in Slo2.1 K+ channels.A point mutation in the human Slo1 channel that impairs its sensitivity to omega-3 docosahexaenoic acid.Atomic determinants of BK channel activation by polyunsaturated fatty acids.BK channel opening involves side-chain reorientation of multiple deep-pore residues.The BK channel: a vital link between cellular calcium and electrical signaling.How to resolve microsecond current fluctuations in single ion channels: the power of beta distributions.Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channelsAn extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate.Molecular mechanisms of Slo2 K+ channel closure.Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel.Keeping you healthy: BK channel activation by omega-3 fatty acidsWhere's the gate? Gating in the deep pore of the BK(Ca) channel.Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel.BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.
P2860
Q26771787-51A47A00-6466-40ED-9884-2A5E4171A85BQ27675587-86E0B6BD-54B1-4253-8AB3-B5B304F2BD40Q34409608-489FB658-3A3C-4DAB-92F6-306FF8A6B74CQ35112968-BA996EE0-D8F6-4B6F-8AC1-550B12048980Q35470532-C8ECBED6-C1FC-4FA1-B63A-6CC72EB2D75BQ35549225-63874EAF-EB61-4030-AB10-4C3A4DE1EB08Q35557265-F9143DED-37F5-4182-9430-2496E0BFCB76Q35789217-7E15787C-1CCA-4DBE-B0A2-D17C3B230F2DQ36087911-491ABF40-DBEA-4A08-A2EC-B17B33877B25Q36166100-261F2A91-266A-461B-8731-39777B4521ECQ36446389-9959AB69-37FB-4BC1-A951-40FE3C149A32Q36712653-FEFAB597-95C4-4DEA-926A-37D1405B18A2Q36923791-E5A999C4-89D7-4CBE-9819-EC5BDAFE5FB9Q37091597-361006DA-FB0D-4CCF-AEE4-549A0373BA6CQ37268772-6F14D4F8-4A45-4886-A890-FB96AEC38E1EQ37268776-051E638C-089C-4F32-8E38-8E77803174B0Q37473820-7B517776-E108-4C54-B075-C3C00B878B26Q37474795-93FF3084-CD41-4D21-8787-F922218E1BF1Q38045185-0B441033-F7D3-4BF0-918C-8F31B21AE1F2Q38586533-278CDC47-A2F6-407B-A690-F2AB6C9C62B1Q38798356-742527C7-8E46-4257-85DC-56F462F7EBFDQ40118449-66C6BA83-5FEB-439B-A68F-1B76A7F34853Q41600565-D2D04473-0835-419F-A505-BA881DEEC3D3Q41640525-83E7ED52-9447-4522-8E1F-CBA737790FF5Q41791327-38EE336C-0644-4CF6-A6DE-00C0CB54670CQ42736179-3D542CB0-6A2F-42D0-AA91-E0763DEEA90EQ47449784-978F6FB7-A80C-44E3-90B5-0D90CE611815Q54698544-9A8BF2EF-CF30-4C3C-AC71-13E2F0DCF276
P2860
Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Charge substitution for a deep ...... mics during BK channel gating.
@ast
Charge substitution for a deep ...... mics during BK channel gating.
@en
type
label
Charge substitution for a deep ...... mics during BK channel gating.
@ast
Charge substitution for a deep ...... mics during BK channel gating.
@en
prefLabel
Charge substitution for a deep ...... mics during BK channel gating.
@ast
Charge substitution for a deep ...... mics during BK channel gating.
@en
P2860
P356
P1476
Charge substitution for a deep ...... mics during BK channel gating.
@en
P2093
Richard W Aldrich
P2860
P304
P356
10.1085/JGP.201110632
P577
2011-07-11T00:00:00Z