Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery
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Spontaneous excitation patterns computed for axons with injury-like impairments of sodium channels and Na/K pumpsBilayer Effects of Antimalarial CompoundsRegulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity.Phytochemicals perturb membranes and promiscuously alter protein function.Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.Small-molecule photostabilizing agents are modifiers of lipid bilayer properties.Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling.A general mechanism for drug promiscuity: Studies with amiodarone and other antiarrhythmicsCharacterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp ScreeningThe cost of living in the membrane: a case study of hydrophobic mismatch for the multi-segment protein LeuT.HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.Phosphoinositides alter lipid bilayer properties.Cucurbitane Triterpenoid from Momordica charantia Induces Apoptosis and Autophagy in Breast Cancer Cells, in Part, through Peroxisome Proliferator-Activated Receptor γ Activation.Assessing smectic liquid-crystal continuum models for elastic bilayer deformations.Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers.Pharmacological distinction between soluble and transmembrane adenylyl cyclases.PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease.Liquid general anesthetics lower critical temperatures in plasma membrane vesicles.Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.Left-shifted nav channels in injured bilayer: primary targets for neuroprotective nav antagonists?Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation.Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels.
P2860
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P2860
Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Thiazolidinedione insulin sens ...... mplications for drug discovery
@ast
Thiazolidinedione insulin sens ...... mplications for drug discovery
@en
type
label
Thiazolidinedione insulin sens ...... mplications for drug discovery
@ast
Thiazolidinedione insulin sens ...... mplications for drug discovery
@en
prefLabel
Thiazolidinedione insulin sens ...... mplications for drug discovery
@ast
Thiazolidinedione insulin sens ...... mplications for drug discovery
@en
P2093
P2860
P356
P1476
Thiazolidinedione insulin sens ...... mplications for drug discovery
@en
P2093
Denise V Greathouse
Hugh C Hemmings
Karl F Herold
Olaf S Andersen
R Lea Sanford
Radda Rusinova
P2860
P304
P356
10.1085/JGP.201010529
P577
2011-08-01T00:00:00Z