Structural regulation of cullin-RING ubiquitin ligase complexes.
about
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) bindingTRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexesStructural basis for autoinhibition and phosphorylation-dependent activation of c-CblRING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitinationBuilding and remodelling Cullin-RING E3 ubiquitin ligasesFunctional diversity and structural disorder in the human ubiquitination pathwayStructure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceA RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligasesSelective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin LigaseThe Structural Basis of Iron Sensing by the Human F-box Protein FBXL5Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin LigasesThe predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradationSignal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97.Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4BUbiquitylation, neddylation and the DNA damage responseA negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiationAn allosteric conduit facilitates dynamic multisite substrate recognition by the SCF(Cdc4) ubiquitin ligaseDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Conserved properties of Drosophila Insomniac link sleep regulation and synaptic functionStructural and functional insights to ubiquitin-like protein conjugation.Crossover localisation is regulated by the neddylation posttranslational regulatory pathway.Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34.Ubiquitination and degradation of the hominoid-specific oncoprotein TBC1D3 is mediated by CUL7 E3 ligaseCrystal structure of KLHL3 in complex with Cullin3Identification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complexMacromolecular juggling by ubiquitylation enzymes.Cullin E3 ligases and their rewiring by viral factorsVprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligasesInactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases.Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2)Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complexThe Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride ChannelsSkp1 Independent Function of Cdc53/Cul1 in F-box Protein HomeostasisShaping the landscape: mechanistic consequences of ubiquitin modification of chromatin.Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.Dbo/Henji Modulates Synaptic dPAK to Gate Glutamate Receptor Abundance and Postsynaptic Response.Cullin RING ligases: glommed by glomulin
P2860
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P2860
Structural regulation of cullin-RING ubiquitin ligase complexes.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Structural regulation of cullin-RING ubiquitin ligase complexes.
@ast
Structural regulation of cullin-RING ubiquitin ligase complexes.
@en
type
label
Structural regulation of cullin-RING ubiquitin ligase complexes.
@ast
Structural regulation of cullin-RING ubiquitin ligase complexes.
@en
prefLabel
Structural regulation of cullin-RING ubiquitin ligase complexes.
@ast
Structural regulation of cullin-RING ubiquitin ligase complexes.
@en
P2093
P2860
P1476
Structural regulation of cullin-RING ubiquitin ligase complexes.
@en
P2093
Brenda A Schulman
Daniel C Scott
David M Duda
Erik S Zimmerman
Matthew F Calabrese
Ning Zheng
P2860
P304
P356
10.1016/J.SBI.2011.01.003
P577
2011-02-01T00:00:00Z