Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease - Wikidata - awgldk - TriplyDB

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

http://www.wikidata.org/entity/Q35157431

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Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2 Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models Potential Roles of Adropin in Central Nervous System: Review of Current Literature The neurology of mTOR Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders Protein Kinases and Parkinson's Disease Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation Neurotrophic effects of a cyanine dye via the PI3K-Akt pathway: attenuation of motor discoordination and neurodegeneration in an ataxic animal model Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease.Out FOXing Parkinson disease: where development meets neurodegeneration.Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons.GT1b-induced neurotoxicity is mediated by the Akt/GSK-3/tau signaling pathway but not caspase-3 in mesencephalic dopaminergic neurons Glutamate controls growth rate and branching of dopaminergic axons.DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.Regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B.Naringin: a protector of the nigrostriatal dopaminergic projection.Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis.Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo.A neuroprotective role for angiogenin in models of Parkinson's disease Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt.The JNK- and AKT/GSK3β- signaling pathways converge to regulate Puma induction and neuronal apoptosis induced by trophic factor deprivation Akt1 mediates neuronal differentiation in zebrafish via a reciprocal interaction with notch signaling Programmed cell death and new discoveries in the genetics of parkinsonism.Intracellular signalling pathways in dopamine cell death and axonal degeneration.Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism.Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling.Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease.Axon degeneration in Parkinson's disease Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease Fate mapping and lineage analyses demonstrate the production of a large number of striatal neuroblasts after transforming growth factor alpha and noggin striatal infusions into the dopamine-depleted striatum Treatment of Parkinson's disease with trophic factors.Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein.Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.Huntington's disease and Group I metabotropic glutamate receptors.

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P2860

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

http://www.wikidata.org/entity/Q35157431

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

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2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@ast

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@en

type

label

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@ast

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@en

prefLabel

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@ast

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@en

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PNAS.0606401103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

@en

P2093

Claire Henchcliffe

http://www.w3.org/2001/XMLSchema#string

Margarita Rzhetskaya

http://www.w3.org/2001/XMLSchema#string

Matthew J During

http://www.w3.org/2001/XMLSchema#string

Nikolai Kholodilov

http://www.w3.org/2001/XMLSchema#string

Ross Bland

http://www.w3.org/2001/XMLSchema#string

Tatyana Kareva

http://www.w3.org/2001/XMLSchema#string

Vincent Ries

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

Neurotrophin signal transduction in the nervous system.

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons

Role for Akt3/protein kinase Bgamma in attainment of normal brain size

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

Cellular survival: a play in three Akts

Regulation of neuronal survival by the serine-threonine protein kinase Akt

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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18757-18762

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scholarly article

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10.1073/PNAS.0606401103

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P433

49

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103

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P577

2006-11-20T00:00:00Z

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6680853

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17116866

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P921

Parkinson's disease

P932

1654135

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