The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome
about
Unwinding and rewinding: double faces of helicase?Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamilyUnpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleasesCell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiencyWerner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsNon-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome StabilityHuman RecQ helicases in DNA repair, recombination, and replication.The role of DNA exonucleases in protecting genome stability and their impact on ageing.Expression of XPG protein in human normal and tumor tissues.Nonenzymatic role for WRN in preserving nascent DNA strands after replication stress.Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathwayDNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals.Yeast RAD2, a homolog of human XPG, plays a key role in the regulation of the cell cycle and actin dynamics.Novel XPG (ERCC5) mutations affect DNA repair and cell survival after ultraviolet but not oxidative stress.The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.TelNet - a database for human and yeast genes involved in telomere maintenance.Ultraviolet radiation: DNA damage, repair, and human disorders
P2860
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P2860
The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@ast
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@en
type
label
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@ast
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@en
prefLabel
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@ast
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@en
P2093
P2860
P356
P1433
P1476
The DNA repair endonuclease XP ...... e defective in Werner syndrome
@en
P2093
Albert R Davalos
J Jefferson P Perry
Judith Campisi
Kelly S Trego
Miaw-Sheue Tsai
Priscilla K Cooper
Sophia B Chernikova
Steven M Yannone
P2860
P304
P356
10.4161/CC.10.12.15878
P577
2011-06-15T00:00:00Z