Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway. - Wikidata - awgldk - TriplyDB

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

http://www.wikidata.org/entity/Q35160414

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Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1 Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65 The Regulation of NF-κB Subunits by Phosphorylation Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human Tumorigenesis PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192 FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence The SH3BGR/STAT3 Pathway Regulates Cell Migration and Angiogenesis Induced by a Gammaherpesvirus MicroRNA.Defining, comparing, and improving iTRAQ quantification in mass spectrometry proteomics data Aberrant regulation of FBW7 in cancer.An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7.Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.A significant risk locus on 19q13 for bipolar disorder identified using a combined genome-wide linkage and copy number variation analysis.Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells.Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.The challenge of the proteome dynamic range and its implications for in-depth proteomics.Proteomics and NF-κB: an update.Oncoprotein stabilization in brain tumors.The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro.GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κB.FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation.Mitogen-Activated Protein Kinase 14 Promotes AKI.Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology.The Role of Ubiquitination in TWEAK-Stimulated Signaling.The hormone-bound vitamin D receptor enhances the FBW7-dependent turnover of NF-κB subunits.Tumor-suppressor NFκB2 p100 interacts with ERK2 and stabilizes PTEN mRNA via inhibition of miR-494 Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase FBXW7: a critical tumor suppressor of human cancers

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Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

http://www.wikidata.org/entity/Q35160414

description

2012 nî lūn-bûn

@nan

2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

@ast

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

@en

type

label

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

@ast

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

@en

prefLabel

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

@ast

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

@en

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Nature Communications

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Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

@en

P2093

Azadeh Arabi

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Dan Grandér

http://www.w3.org/2001/XMLSchema#string

Daniel Bandarra

http://www.w3.org/2001/XMLSchema#string

Gutian Xiao

http://www.w3.org/2001/XMLSchema#string

Ingrid Ariës

http://www.w3.org/2001/XMLSchema#string

Johan Johansson

http://www.w3.org/2001/XMLSchema#string

Karim Ullah

http://www.w3.org/2001/XMLSchema#string

Monique L Den Boer

http://www.w3.org/2001/XMLSchema#string

Moritz Haneklaus

http://www.w3.org/2001/XMLSchema#string

Olle Sangfelt

http://www.w3.org/2001/XMLSchema#string

P2860

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

The NF-kappa B and I kappa B proteins: new discoveries and insights

Significance analysis of microarrays applied to the ionizing radiation response

Ongoing and future developments at the Universal Protein Resource

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

A fourth IkappaB protein within the NF-kappaB signaling module

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases

A cell cycle regulatory network controlling NF-kappaB subunit activity and function

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

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976

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10.1038/NCOMMS1975

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3

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Katja Pokrovskaja Tamm

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2012-01-01T00:00:00Z

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230619630

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22864569

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4354031

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